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Effect of chemical agents containing green tea and hyaluronic acid in controlling inflammation and bacterial plaque around teeth and implants.

Effect of chemical agents containing green tea and hyaluronic acid, in dentifrice and mouthwash formulations, on periodontal and peri-implant clinical parameters. A Randomized Controlled clinical trials.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-7scgp3h
Enrollment
Unknown
Registered
2021-10-11
Start date
2021-08-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mucositis

Interventions

This study will test different oral hygiene devices (Dentifrice and mouthwashes) based on green tea and hyaluronic acid in patients with implant-supported dentures. In experiment 1, sixty patients wit
Toothpaste Group 1 - Colgate Total 12
Toothpaste Group 2 – Crest
Vehicle Group: test toothpaste without hyaluronic acid and green tea. In experiment 2, forty-five patients with total prostheses supported over implants will be divided into 3 groups with 15 patients
Positive Control Group – 0.12% Chlorhexidine
Vehicle Group – Test mouthwash without hyaluronic acid and green tea.
E02.547.600
SP8.473.654.412.052.016

Sponsors

Universidade Federal de Uberlândia
Lead Sponsor
New Detal Care LTDA
Collaborator

Eligibility

Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with dental implant in partial or single rehabilitation with permanent dentures installed for at least 6 months; age group from 18 to 60 years old; systemically healthy

Exclusion criteria

Exclusion criteria: Smokers; uncontrolled diabetics; history of radiotherapy or chemotherapy

Design outcomes

Primary

MeasureTime frame
The use of oral hygiene devices containing green tea and hyaluronic acid will be able to reduce inflammation of the peri-implant mucosa by 10% compared to the use of chlorhexidine-based mouthwashes and fluorine-based toothpastes.—

Secondary

MeasureTime frame
The use of oral hygiene devices containing green tea and hyaluronic acid will be able to reduce the amount of biofilm by 10% compared to the use of chlorhexidine-based mouthwashes and fluorine-based toothpastes.—

Countries

Brazil

Contacts

Public ContactGuilherme Oliveira
guilherme.lopesoliveira@ufu.br+55(16)982562421

Outcome results

None listed

Source: REBEC (via WHO ICTRP)