Rehabilitation
Conditions
Interventions
This is a randomized clinical trial. The randomization process was carried out through a simple draw in which 30 control cards and 30 intervention cards were inserted into an envelope. The draw will t
E02.779.474
Sponsors
Universidade Estadual de Campinas
Universidade Estadual de Campinas
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients of both sexes will be included; aged 18 years or over; clinical and surgical patients admitted to the HC/UNICAMP Adult ICU; without sedatives; patients with ICU-acquired muscle weakness with MRC less than or equal to 48; collaborative patients; with a Glasgow Coma Scale score greater than or equal to 8, with a motor response score equal to 6, for application of the MRC scale and surface electromyography; hemodynamic stability with mean arterial pressure greater than 65 mmHg with minimal or no use of vasoactive drugs; peripheral oxygen saturation greater than or equal to 90% with FiO2 less than or equal to 60% and PEEP less than or equal to 10cmH2O; patients and/or legal representatives who agree to participate in this study and sign the Informed Consent Form
Exclusion criteria
Exclusion criteria: Hemodynamic instability; recent acute myocardial infarction or cardiac arrhythmias proven by electrocardiogram; use of sedatives; use of high parameters in MV; fractures of lower limbs or upper limbs; use of external fixator; amputation of lower limbs or upper limbs; orthopedic alterations that limit orthostatism; significant calcaneal eschar; patients with deep vein thrombosis; patients with significant thrombocytopenia with values below 50. 000; hemiplegic patients; patients after spinal cord trauma; patients with neuromuscular diseases; patients with intracranial pressure monitoring and/or external ventricular shunt; patients with intra-aortic balloon; patients with fever greater than or equal to 37.8°C
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| At the end of the study, it is expected that the daily passive orthotic protocol will have a beneficial effect on the strength and muscle mass of patients with intensive care unit (ICU)-acquired weakness | — |
Secondary
| Measure | Time frame |
|---|---|
| It is believed that there is an increase in the values of Medical Research Council (MRC), root mean square (RMS), thigh circumference, thickness, echogenicity and cross-sectional area of the quadriceps after performing a passive orthostatism protocol for ten consecutive days in patients with ICU-acquired weakness. To assess the impact of these changes on the length of stay and discharge/death outcomes of the patients | — |
Countries
Brazil
Contacts
Public ContactMelissa Sibinelli
Universidade Estadual de Campinas
Outcome results
None listed