Skip to content

Transcranial Magnetic Stimulation as a Treatment for Primary Progressive Aphasia

Case series: Transcranial Magnetic Stimulation for the treatment of patients with Primary Progressive Aphasia

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
REBEC
Registry ID
RBR-7rvw6cd
Enrollment
Unknown
Registered
2023-11-22
Start date
2023-07-31
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aphasia, Primary Progressive

Interventions

This is a case series with a group of 6 patients who will undergo 30 sessions of Transcranial Magnetic Stimulation over 6 weeks. A high frequency EMT protocol will be performed on the left Dorsolatera
E02.621.820

Sponsors

Instituto de Psiquiatria da Universidade Federal do Rio de Janeiro
Lead Sponsor
Instituto de Psiquiatria da Universidade Federal do Rio de Janeiro
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Diagnosis of Aphasia,Primary Progressive - APP(logopenic, grammatical or semantic subtypes) based on clinical evaluation and speech-language pathology evaluation; be able to read, understand and sign the consent form to participate in the research;patients of both genders

Exclusion criteria

Exclusion criteria: Contraindication to Transcranial Magnetic Stimulation: history of epilepsy, traumatic brain injury, metal implant in the head; patients under judicial guardianship

Design outcomes

Primary

MeasureTime frame
As a primary outcome of the study, it is expected to find a better performance of the participants in relation to language through the Montréal-Toulouse battery (MTL Brasil) and through the increase of the Addenbrooke (ACE-R) scores

Secondary

MeasureTime frame
Regarding the secondary outcomes, we expect a reduction in the scores of the Geriatric Depression Scale - short version (GDS-15), reduction in the scores of the Assessment Scale of Psychosocial Impact of the Diagnosis of Dementia (AIPDD), of the Functional Activities Questionnaire (PFEFFER) and the Neuropsychiatric Inventory (NPI)

Countries

Brazil

Contacts

Public ContactValeska Rodrigues

Instituto de Psiquiatria da Universidade Federal do Rio de Janeiro

vm@valeskamarinho.med.br+55 21 3938-0500

Outcome results

None listed

Source: REBEC (via WHO ICTRP)