Parkinson disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosis of idiopathic Parkinson´s disease confirmed by a movement disorders specialist in accordance with Parkinson’s Disease Society Brain Bank diagnostic criteria; both genders; age over 50 years; disease staging between 1.5 and 3 according to the modified Hoehn and Yahr scale; undergoing regular and stable pharmacological treatment; Mini-Mental State Examination score major ou equal to 24; no other associated neurological, musculoskeletal and/or cardiorespiratory diseases and the ability to walk independently; having a smartphone or computer and access to internet; knowledge about or available assistance on how to make video calls; and the ability to participate and provide written informed consent
Exclusion criteria
Exclusion criteria: Diagnosis of atypical Parkinson´s disease; neuropsychiatric comorbidities; inability to walk 10 meters; presence of severe dyskinesia that prevents the participant from sitting in a chair; not understanding any of the training protocol stages and experiencing severe pain and/or discomfort that precludes performing the proposed activities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is aimed to quantify the improvement of functional lower extremity strength and identify movement strategies used to complete transitional movements through the Five Times Sit-to-Stand (5TSTS) Test, measuring the time (seconds). It is expected to reach values lower than 0.16 seconds in the post-intervention assessment, since values higher than this cut-off point indicate risk of falls | — |
Secondary
| Measure | Time frame |
|---|---|
| It is aimed to verify the reduction of fear of falling assessed by Falls Efficacy Scale (FES-I), with reduction in total score ponctuation of at least 6.8% on pre- and post-intervention measurements;An improvement in the quality of life assessed by the Parkinson´s Disease Questionnaire (PDQ-39) is expected, with a reduction in the total score punctuation by at least 6 points in the total score of the scale after the post-intervention measurement, which can be considered a minimum meaningful change;It is aimed to minimize the symptoms of depression and anxiety assessed by the Hospital Anxiety Depression Scale (HADS). The minimally important change for HADS-A is 1.84 and for HADS-D is 1.72 ;It is aimed to improve the signals and symptoms of Parkinson´s disease related to activities of daily life (ADL) assessed by Movement Disorders Society (MDS) – Unified Parkinson´s Disease Rating Scale part two (MDS-UPDRS II) with total score reduction reflecting at least 8.2%, the minimum detectable change, on pre- and post-intervention measurements;It is aimed to improve the cognition assessed by Verbal Fluency (VF) Test increasing the quantity of words informed by the examined reflecting of at least 10% on pre- and post-intervention measurements | — |
Countries
Brazil
Contacts
Universidade Estadual de Londrina