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Influence of Dextroketamine on Brain Electrical Activity Monitoring during Total Venous Anesthesia

Influence of Dextroketamine on Electroencephalogram during Total Venous Anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-7qmdrhy
Enrollment
Unknown
Registered
2023-01-11
Start date
2022-08-15
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Electroencephalography

Interventions

This is a triple-blind, randomized, controlled, 5-arm interventional study. A total of 40 participants were randomly allocated into five groups of 8 using a restricted (sequential) randomization metho

Sponsors

Hospital São Carlos
Lead Sponsor
Hospital São Carlos
Collaborator

Eligibility

Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: patients both genders; undergoing elective operations under general anesthesia; physical status P1 (American Society of Anesthesiologists); ages between 20 and 45 years and; body mass indexes between 21 and 26 kg.m-2

Exclusion criteria

Exclusion criteria: Patients with neurological disease; recent use of drugs that may alter the electroencephalogram.

Design outcomes

Primary

MeasureTime frame
Expected Outcome: To evaluate the influence of different doses of Dextroketamine during total venous anesthesia on bispectral index and facial electromyographic activity, monitored with a BIS Vista™ monitor version 3.5, based on a statistically significant variation, with p- value less than 0.05. ;Outcome: It was observed that the parameters bispectral index and facial electromyographic activity did not present significant changes in this model of total venous anesthesia with the doses of Dextroketamine administered.

Secondary

MeasureTime frame
Secondary outcomes are not expected.

Countries

Brazil

Contacts

Public ContactBruno Meireles

Hospital São Carlos

brunormeireles@gmail.com+55(85)4009-1278

Outcome results

None listed

Source: REBEC (via WHO ICTRP)