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Use of Dental Graft for Alveolar Repair after lower third molar Extraction

Use of Autogenous Dental Grafting for Alveolar Repair: double-blind randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-7q7vw68
Enrollment
Unknown
Registered
2024-11-28
Start date
2023-10-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alveolar Bone Grafting

Interventions

This is a two-arm, double-blind, split-mouth randomized controlled clinical study. Experimental group: 10 patients with bilateral lower third molars undergoing extraction followed by dentin grafting i
3) osteotomy with minimal bone wear and odontosection using surgical motor and drills under irrigation of sterile 0.9% saline solution
4) tooth avulsion
5) osteoplasty and cleaning of the surgical site
6) repositioning the flap and suturing with 4-0 nylon thread. The suture must be removed 7 (seven) days after surgery. The preparation and processing of the graft will be done with the aid of tungsten

Sponsors

Faculdade de Odontologia de Pernambuco/ UPE
Lead Sponsor
Departamento de Pós-Graduação em Cirurgia e Traumatologia BucoMaxiloFacial
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Aealthy adult patients = 18 years old; who need the removal of two lower third molars with adjacent second molars; who have impacted and mesioangulated lower third molars with similar positioning with the contralateral side; who have continuity of the alveolar walls after extraction; who have gingiva enough keratinized tissue to cover the grafted bone; and who spontaneously accept to participate in this research protocol and sign the Informed Consent Form

Exclusion criteria

Exclusion criteria: Patients with erupted or semi-impacted mandibular third molars with distoangular, vertical and horizontal positioning; with endocrine/metabolic disorders that may affect bone regeneration; with acute infection; periapical lesion; endodontic treatment; root caries; cystic lesion or tumor associated with teeth; who take/have taken bisphosphonates; smokers; who present loss of one or more alveolar walls after tooth extraction and who are unable to understand the purpose of the study or who do not accept the methodology employed

Design outcomes

Primary

MeasureTime frame
It is expected to find a mean difference in edema, pain, postoperative trismus, probing depth, clinical attachment level and gingival recession, height, width and alveolar volume between the groups studied.

Secondary

MeasureTime frame
No secondary outcomes are expected

Countries

Brazil

Contacts

Public ContactBelmiro Vasconcelos

Faculdade de Odontologia de Pernambuco/ UPE

belmiro.vasconcelos@upe.br+55 81 98886-8677

Outcome results

None listed

Source: REBEC (via WHO ICTRP)