Burning Mouth Syndrome Stomatognathic Diseases
Conditions
Interventions
This is an open-label, randomized, controlled clinical trial with four arms, in which 80 participants who meet the eligibility criteria will be allocated by simple randomization (draw) into 4 groups.
s recommendations, which consists of punctual applications with infrared laser (L2) (100mW power, 808 nm, 4 joules of energy/40 seconds) in the affected area, maintaining a one-centimeter distance bet
Sponsors
Universidade Federal do Rio Grande do Norte
Universidade Federal do Rio Grande do Norte
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Individuals of both sexes over 18 years of age; Individuals who presented with a burning sensation in the oral mucosa or recurrent dysesthesia, daily for more than two hours a day, for more than three months, without clinically evident causal lesions; Individuals who present with a burning sensation in the mouth or recurrent dysesthesia, even if they have salivary alterations or some systemic alteration that may be related to the symptoms; patients who are not undergoing any other type of treatment for burning mouth for at least three months at the time of inclusion in the study; Individuals who are physically able to attend the study tests
Exclusion criteria
Exclusion criteria: Individuals with Sjögren's syndrome who presented with alterations and/or lesions in the oral mucosa, such as erosive lichen planus, ulcerations, geographic tongue, infections, allergic reactions, trauma, and lesions caused by physical or chemical agents; individuals with a known allergy to pepper and its derivatives; pregnant or breastfeeding women; patients with severe neurological or psychiatric diseases that could interfere with pain perception or adherence to the protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: Topical capsaicin 0,001% used alone is expected to be more effective than low-level laser therapy in reducing painful symptoms in patients suffering from burning mouth syndrome, which will be assessed using the visual analog pain scale before, during, and after treatment. ;Outcome found 1: Topical capsaicin 0,001% used alone proved to be as effective as low-level laser therapy. And, when combined, the reduction in symptoms is already significant from the second week of treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcomes are expected. | — |
Countries
BR
Contacts
Public ContactBrenda Ferreira
Universidade Federal do Rio Grande do Norte
Outcome results
None listed