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Acute effects of motor rehabilitation in stroke survivors through resistance training and neuromodulation

Motor rehabilitation in stroke survivors with severe functional impairments through unilateral eccentric training combined with cortical neuromodulation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-7pxmfjc
Enrollment
Unknown
Registered
2025-04-09
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke, not specified as haemorrhage or infarctio

Interventions

This study will be a randomized clinical controlled trial with a cross-over design. Fifteen patients (males and females), with more than 18 years old, who had a stroke episode more than 6 months ago w
E02.760.169.063.500.387.875
E02.331.750
L01.224.160.875

Sponsors

Instituto de Física Gleb Whatagin
Lead Sponsor
Instituto de Física Gleb Whatagin
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who suffered a stroke (type 1); patients who have severe hemeparesis as a consequence of the stroke; both female and male patients; patients above 18 years old

Exclusion criteria

Exclusion criteria: Patients who have any type of metal inside their body (pins, pacemakers, metal prostheses, revolver bullets); patients who have any musculoskeletal injury on the affected or unaffected limbs; patients who had previous conditions such as seizures, head trauma, hearing problems and cochlear impalants

Design outcomes

Primary

MeasureTime frame
We expect that differences will occur among conditions, in which conditions (iii) and (iV) will lead to greater increases in strength, power, muscle activation and active range of motion of the paretic limbs from before to after the intervention compared to the other conditions;We expect that differences will occur among conditions, in which condition (iii) and (iv) will lead to greater increases in cortical connectivity and corticospinal excitability, and reductions in pre-synaptic and intracortical inhibition, which will facilitate the neural pathway for motor gains to occur on the paretic muscle groups from before to after the intervention compared to the other conditions

Secondary

MeasureTime frame
We expect that differences will occur among conditions, in which conditions (iii) and (iv) will lead to greater changes on the same parameters assessed on the non-paretic limbs from before to after the intervention compared to the other conditions;We expect the greatest changes to occur for all measurements when tDCS is applied on the motor cortex hemisphere not affected (contralesionsal) by the stroke episode

Countries

Australia, Brazil

Contacts

Public ContactCássio Víctora Ruas

Universidade Estadual de Campinas

c.victoraruas@ecu.edu.au+55(51)999087088

Outcome results

None listed

Source: REBEC (via WHO ICTRP)