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Evaluation of Photodynamic Therapy in patients with Diabetes

Evaluation of Chlorhexidine gel associated with Photodynamic Therapy in the treatment of Chronic Periodontitis in patients with Diabetes

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-7pn5prj
Enrollment
Unknown
Registered
2024-04-24
Start date
2024-01-19
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetes mellitus

Interventions

This is a clinical, microbiological, longitudinal, split-mouth study. The study will be held at the Dental Clinic of the Department of Specific Training of the Universidade Federal Fluminense and mult
D02.078.370.141.100
E02.594

Sponsors

Universidade Federal Fluminense
Lead Sponsor
Universidade Federal Fluminense
Collaborator

Eligibility

Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Participants over 18 years old; type 2 diabetics; periodontal disease with pockets with probing depth greater than 5 mm

Exclusion criteria

Exclusion criteria: hypersensitivity to the components of chlorhexidine gel or methylene blue and laser therapy and any evidence of systemic modifying factors of periodontal disease; except diabetics; osteoporosis types I and II; alcoholism; acquired or induced immunosuppression; any change described in the literature as potentially modifying the profile of periodontal disease; physical/emotional stress; medications that influence periodontal tissues. Samples from pregnant or lactating women; participants who have taken antibiotics in the last 6 months; clinical manifestations of oral candidosis; anti-inflammatories or hormone replacement therapy; and/or who have received periodontal treatment in the last six months prior to the procedure will be excluded

Design outcomes

Primary

MeasureTime frame
It is expected to find an average difference in periodontal pocket smaller than five millimeters

Secondary

MeasureTime frame
It is expected to find similar results to periodontal treatment in terms of clinical response and reduction in clinical parameters after periodontal treatment for both sites evaluated, test and placebo.

Countries

Brazil

Contacts

Public ContactGabriela Da Cruz Galhardo Camargo

Universidade Federal Fluminense

gabrielacruz@id.uff.br+55 22 2528-7168

Outcome results

None listed

Source: REBEC (via WHO ICTRP)