Anterior cruciate ligament
Conditions
Interventions
A triple blind randomized clinical trial was performed in a sample of patients diagnosed with chronic knee instability with indication for surgical treatment, whose size was estimated in relation to t
date of surgery, the operated side, the group to which the patient belonged (I, II, III, IV), ischemia time during surgery, heart rate (HR) and blood pressure (BP) in the so-called T0 (immediately aft
Group II (n = 12) 20 ml 0.5% bupivacaine
Group III (n = 12) 20 ml 0.5% bupivacaine + 0.1 mg epinephrine
Group IV (n = 12) 20 ml 0.9% SF + 0.1 mg epinephrine.
Pain intensity was evaluated by EV, and the painful stimulus caused by knee flexion at 45 degrees, repeated three times, measured with the aid of
Drug
E01.370.600.550.324
Sponsors
Fundacao Hospital Adriano Jorge
Fundacao Hospital Adriano Jorge
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: The following inclusion criteria were adopted: diagnosis of chronic knee instability; older than 18 years; classification of physical status according to the American Society of Anesthesiologists (ASA) I and II scale; no local and systemic inflammatory diseases; isolated injuries of the anterior cruciate ligament (ACL only), with no history of fractures or previous knee surgery; use as a graft the medial flexor tendons; operated by the principal researcher and his team
Exclusion criteria
Exclusion criteria: Exclusion criteria were: skeletally immature patients; chondral lesions larger than 2 cm2; associated surgical procedures such as osteotomies, and other ligaments; patients without clinical conditions, hypertensive, with coagulopathies, pregnant; chronic use of anticoagulants; analgesic use up to 24 h before the surgical procedure; patients who refused to sign the consent form; patients not operated at the institution: the anesthesiologist's refusal to follow the project protocol and patients who declared themselves indigenous; older than 65 years old
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The presentation of the expected primary end point was to evaluate postoperative pain decrease in patients who received intra-articular analgesic solutions after anterior cruciate ligament reconstruction;Outcome was decreased pain in patients receiving analgesic solutions | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes Find out which analgesic solution is most effective in controlling postoperative pain; Observe in which periods there is better control of postoperative pain; Identify the potential systemic adverse effects of these solutions; Check the amount of analgesic and anti-inflammatory adjuvant medications; Check the systemic adverse effects caused by analgesic and anti-inflammatory medications and whether or not they are related to the solutions;We found no differences between the solutions, epinephrine does not add advantage in pain control, there were no differences in the use of oipoids in the studied groups (with medications), no differences in adverse effects. | — |
Countries
Brazil
Contacts
Public ContactMarcos Souza Leao
Fundacao Hospital Adriano Jorge
Outcome results
None listed