Ventilator-associated pneumonia
Conditions
Interventions
A randomized, double-blind, controlled trial will be conducted to evaluate the oral care of critically ill mechanically ventilated patients with different antiseptics already used in intensive care un
Drug
Procedure/surgery
N06.850.780.200.450.150.160
H02.403.720.750
Sponsors
Universidade Federal de Uberlândia
Universidade Federal de Uberlândia
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients admitted to the Intensive Care Unit of the Federal University of Uberlândia Hospital das Clínicas from 2019 to 2020; dependent on mechanical ventilation for more than 48 hours; regardless of gender; over 18 years old; head trauma victim
Exclusion criteria
Exclusion criteria: Patients under 18 years of age; undergoing endotracheal intubation 48 hours before admission; mechanical ventilation dependents before 48 hours; diagnosis of pneumonia prior to admission; burns; pregnant women; patient in palliative care; patients with restrictive measures; brain death at presentation; if the research participant is identified
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate the number of participants who died during hospitalization in each of the three groups in order to compare the all-cause mortality rate in each group;To assess the presence or absence of ventilator-associated pneumonia during intensive care unit admission to compare which antiseptic prevented this outcome further | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess costs by collecting data on days of extubation time, length of stay in the intensive care unit and length of hospital stay, in addition to the proportion of discharge to home and rehabilitation clinic;Assess if there were mechanical ventilation events during the patient's hospitalization, collecting data from the physical examination chart and complementary exams that indicate and diagnose lung lesions, respiratory distress syndrome and infections;Assess if any of the antiseptics caused more local damage by identifying data recorded in medical or nursing evolution of oral ulcers, tooth damage, allergic reactions, or bleeding | — |
Countries
Brazil
Contacts
Public ContactPaula Vieira
Universidade Federal de Uberlândia
Outcome results
None listed