Obesity
Conditions
Interventions
This is an open-label crossover clinical trial without the use of medication, involving a total of 16 women with obesity. Group 1: 16 participants received 20 grams per day of macadamia nuts (Macadami
Sponsors
Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo
Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Women aged between 18 and 45 years; Women with a body mass index between 30.0 kg/m² (kilograms per square meter) and 39.9 kg/m² (kilograms per square meter), classified as having grade 1 and grade 2 obesity
Exclusion criteria
Exclusion criteria: Use of medications for the treatment of hyperlipidemia; with a diagnosis of hypertension, type 2 diabetes, dyslipidemia, and metabolic syndrome (self-reported); presence of diseases and/or history of surgeries that compromise nutrient absorption (self-reported); use of vitamin and/or mineral supplements; use of supplements containing fatty acids; use of supplements containing any amino acids; being pregnant and/or participating in another clinical study; undergoing diet therapy for weight loss; being a smoker and/or consuming alcohol; having a food allergy to nuts or peanuts; regular consumption of nuts or peanuts in the diet (in the last 3 months); intense physical activity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find changes in plasma fatty acid profile, assessed by gas chromatography, including oleic acid, linoleic acid, and palmitoleic acid, evaluating the effects of macadamia nut and peanut intervention in women with obesity | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find changes in plasma malondialdehyde (MDA) levels, assessed through specific laboratory analyses, evaluating the effects of macadamia nut and peanut intervention in women with obesity;It is expected to find changes in plasma total antioxidant capacity (CAT), assessed through specific laboratory analyses, evaluating the effects of macadamia nut and peanut intervention in women with obesity;It is expected to find changes in plasma superoxide dismutase (SOD) levels, assessed through specific laboratory analyses, evaluating the effects of macadamia nut and peanut intervention in women with obesity;It is expected to find changes in plasma reduced glutathione (GSH) levels, assessed through specific laboratory analyses, evaluating the effects of macadamia nut and peanut intervention in women with obesity | — |
Countries
Brazil
Contacts
Public ContactGizela Junqueira
Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo
Outcome results
None listed