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Comparative of differents protocols of low level laser therapy as prevent of oral mucositis in patients undergoing bone marrow transplant

Comparative of differents protocols photobiomodulation as prevent of oral mucositis in patients undergoing hematopoietic stem cell transplantation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-7nww56
Enrollment
Unknown
Registered
2019-12-17
Start date
2018-09-12
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mucositis

Interventions

60 patients undergoing hematopoietic stem cell transplantation will be randomized and allocated into two groups: active control group: low-power laser with intraoral application (inside the mouth) and
E02.594.540

Sponsors

A.C. Camargo Cancer Center
Lead Sponsor
A.C. Camargo Cancer Center
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Voluntary patients undergoing hematopoietic stem cell transplantation; of both sexes; from than 18 years.

Exclusion criteria

Exclusion criteria: Previously transplanted hematopoietic stem cell patients.

Design outcomes

Primary

MeasureTime frame
The extraoral photobiomodulation protocol was as effective as an intraoral photobiomodulation for oral mucositis prevention. In addition, extraoral photobiomodulation decreased the time of photobiomodulation session compared to intraoral protocol and was more effective for oral mucositis situated on buccal mucosa than intraoral protocol.—

Secondary

MeasureTime frame
As extraoral as intraoral photobiomodulation protocols maintained low the pain levels (intensity and duration) related to mucositis.—

Countries

Brazil

Contacts

Public ContactMariana;Fábio Ramos Pinto;Alves

A.C. Camargo Cancer Center;A.C. Camargo Cancer Center

maribitu18@gmail.com;falves@accamargo.org.br+55087999274808;+5501121895129

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 23, 2026