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Visual Characteristics of Cholesterol Plaques in Patients with Myocardial Infarction: Contemporary Optical Coherence Tomography Findings

Morphology and Phenotype Characteristics of Atherosclerotic Plaque in Patients with Acute Coronary Syndrome: Contemporary Optical Coherence Tomography Findings - : Plaque Characteristics by Optical Coherence Tomography

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-7nqsm5
Enrollment
Unknown
Registered
2020-06-22
Start date
2012-06-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Coronary Syndrome

Interventions

Contemporary in vivo high-resolution optical coherence tomography (OCT) findings in patients with acute coronary syndrome (ACS) are scarce and subject of controversy. We sought to evaluate plaque morp
Other
E01.370.350.589.249.500

Sponsors

Hospital Israelita Albert Einstein
Lead Sponsor
Hospital Israelita Albert Einstein
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Acute Coronary Syndrome;Optical Coherence Tomography pre-stent

Exclusion criteria

Exclusion criteria: Cases with poor image quality;imaging artifacts;in-stent restenosis;images from non-culprit lesions;pós-stent images.

Design outcomes

Primary

MeasureTime frame
Describe the morphology of the microstructures present in the plates verified by the method of visualization of cholesterol crystals, neovascularization, spotty calcification, calcified nodules and thrombi documented by optical Coherence Tomography using the software QCU-CMS version 3.0, LKEB, Leiden University, the Netherland and presented as a percentage parameter from the finding of statistical difference;Describe the presence of fibrotic plaque, thick-layered fibroateroma, thin-layered, fibrocalcified and fibrolipidic fibroateroma documented by optical Coherence Tomography using the QCU-CMS version 3.0, LKEB, Leiden University, the Netherland software and presented as a percentage parameter a from the finding of statistical difference.—

Secondary

MeasureTime frame
To identify the predictive factors for plaque rupture and thin-cap fibroatheroma by the method of crossing data from patients' medical records and their clinical condition presented as a percentage parameter based on the finding of statistical difference.;Describe the clinical, demographic and previous use of medications using the method of retrospective analysis of patients' medical records presented as a percentage parameter based on the finding of statistical difference.;Quantitatively describe (cavity area, proximal reference, distal reference, minimum luminal area, cavity length, CASS) the characteristics of atheromatous plaques analyzed using the susceptive measurement method in the QCU-CMS version 3.0, LKEB, Leiden University, the Netherland software presented as a percentage parameter from the finding of statistical difference.—

Countries

Brazil

Contacts

Public ContactADRIANO CAIXETA

Hospital Israelita Albert Einstein

adriano.caixeta@einstein.br+55-11-21510434

Outcome results

None listed

Source: REBEC (via WHO ICTRP)