Tubal Pregnancy
Conditions
Interventions
This is an open study, with block randomization (blocks of 4 patients). Intervention group: 90 pacients diagnosed with ectopic pregnancy will be treated with endovenous Methotrexate, in single dose of
Sponsors
Universidade Federal do Paraná
Universidade Federal do Paraná
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Stable patients diagnosed with ectopic pregnancy; beta-hCG levels below 5000 mU/mL; unruptured gestacional sac/mass; gestacional sac/mass below 4cm of length; no sign of fetal heartbeat on the ultrasound
Exclusion criteria
Exclusion criteria: Patients that don't fill the criteria for clinical treatment; patients who don't agree with the Informed Consent Form after reading and comprehending it
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We hope to find a reduced proportion of cases with gestacional sac rupture with endovenous administration of methotrexate, by verifyng at least 5% difference between control and intervention groups. | — |
Secondary
| Measure | Time frame |
|---|---|
| We hope to observe similar rates of collateral offects between control and intervention groups, assessed by laboratory tests, verifying the safety of the new treatment method. | — |
Countries
Brazil
Contacts
Public ContactRafael Bruns
Universidade Federal do Paraná
Outcome results
None listed