Pulmonary collapse
Conditions
Interventions
This is a randomized controlled clinical trial. With the Control group, with a total number of participants of 17 individuals, the Control group participants received three daily physical therapy sess
Sponsors
Universidade Federal de Juiz de Fora
Hospital Santa Casa de Misericórdia de Juiz de Fora
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Participants aged 18 or over will be included; on mechanical ventilation between 12 and 48 hours; not participating in a palliative care program.
Exclusion criteria
Exclusion criteria: Hemodynamic instability (heart rate > 130 bpm and/or mean arterial pressure < 60mmHg); severe bronchospasm; undrained pneumothorax; pulmonary hemorrhage; thoracic trauma; thoracic surgery performed in the last 24 hours; patients transferred to another hospital.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected primary outcome 1: Evaluate the increase in the value of static lung compliance after the intervention, verified by performing an inspiratory pause during mechanical ventilation and the result of the tidal volume divided by the plateau pressure minus the positive end-expiratory pressure, from an increase of at least 10% in measurements at 4 (four) time points: initial assessment, after the standard protocol, after the intervention and 30 minutes after the intervention. Metric: ml/cmH2O | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected secondary outcome 1: Evaluate the increase in the value of dynamic lung compliance after the intervention, verified by performing an inspiratory pause during mechanical ventilation and the result of the tidal volume divided by the peak pressure minus the positive end-expiratory pressure, from an increase of at least 10% in measurements at 4 (four) time points: initial assessment, after the standard protocol, after the intervention and 30 minutes after the intervention. Metric: ml/cmH2O.;Expected secondary outcome 2: Evaluate the reduction in the value of airway resistance after the intervention, verified by performing an inspiratory pause during mechanical ventilation and the result of the peak airway pressure minus the plateau pressure divided by the inspiratory flow of the constant type, from a reduction of at least 10% in measurements at 4 (four) moments: initial assessment, after the standard protocol, after the intervention and 30 minutes after the intervention. Metric: cmH2O/l/min.;Expected secondary outcome 3: Evaluate the increase in the value of pulse oxyhemoglobin saturation after the intervention, verified through multiparametric monitoring via pulse oximeter, from an increase of at least 10% in measurements at 4 (four) moments: initial assessment, after the standard protocol, after the intervention and 30 minutes after the intervention. Metric: percentage.;Expected secondary outcome 4: Evaluate the reduction in the number of days on mechanical ventilation in the intervention group, verified through the evaluation of medical records and monitoring of the clinical evolution of patients, from a reduction of at least 10% measured from the date of hospital discharge or death. Metric: days.;Expected secondary outcome 5: Evaluate the increase in the absolute number and percentage of successes in weaning from mechanical ventilation in the intervention group, verified through the evaluation of medical records and monitoring of the clinical evolution of t | — |
Countries
Brazil
Contacts
Public ContactKarina Silva
Hospital Santa Casa de Misericórdia de Juiz de Fora
Outcome results
None listed