Pain Postoperative
Conditions
Interventions
60 participants will undergo knee arthroscopy to correct anterior cruciate ligament injury, randomized in the experimental group and control group, each with 30 patients who will receive pregabalin or
Drug
Procedure/surgery
E01.370.600.550.324
Sponsors
Hospital São Domingos
Universidade Federal de São Paulo - Unifesp
Eligibility
Inclusion criteria
Inclusion criteria: Patients diagnosed with chronic knee instability; patients older than 18 years; physical status classification according to the scale of the American Society of Anesthesiologists (ASA) I and II; without local and systemic inflammatory diseases; isolated lesions of the anterior cruciate ligament (no other knee ligaments); no history of fractures in the knee region; absence of previous surgeries in the knee region; operated by the orthopedist of the team; ability to read, understand and agree to the inclusion of your data in this research.
Exclusion criteria
Exclusion criteria: Skeletally immature patients; chondral lesions greater than 2 cm2; associated surgical procedures, such as osteotomies, and other knee ligaments; neurological, muscular, rheumatologic, neoplastic or infectious diseases that could provoke some type of joint involvement (gout, multiple myeloma, psoriasis, lymphoma, Paget's disease, rheumatoid arthritis, chronic renal failure, osteomyelitis, ankylosing spondylitis, systemic lupus erythematosus); patients without clinical conditions, hypertensive, with coagulopathies, pregnant women; chronic use of anticoagulants; use of analgesics up to 24 h before the surgical procedure; patients who refused to sign the EHIC; patients not operated at the São Domingos Hospital; refusal or impossibility of the patient to perform the postoperative rehabilitation; non-acceptance of the anesthesiologist in following the protocol of the project; patients allergic to the medications used in the protocol; patients who declared themselves indigenous.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To verify the efficacy of peri-operative pregabalin during the period of 7 days before and 7 days later in the control of postoperative pain through the use of pain scales from the difference of 2 points in the scale in patients submitted to correction of knee ligament by arthroscopy. | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate new methods of minimizing or abolishing postoperative pain in patients submitted to knee arthroscopy, after using pain scales with a difference of two points between the scales. | — |
Countries
Brazil
Contacts
Public ContactPlinio Leal
Hospital São Domingos
Outcome results
None listed