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Assessment of heart health and metabolism in Menopausal women using Isoflavones: a control group study

Cardiovascular evaluation and metabolic profile of women in Menopause using Daidzein and Genistein: a placebo-controlled randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-7mpnx6t
Enrollment
Unknown
Registered
2025-02-17
Start date
2025-03-03
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Menopause

Interventions

This is a randomized, double-blind, crossover, placebo-controlled clinical trial. A total of 60 women who meet the eligibility criteria will be included in the research. The experimental group will co
G07.203.300.456

Sponsors

Fundacao Universidade de Pernambuco
Lead Sponsor
Fundacao Universidade de Pernambuco
Collaborator

Eligibility

Sex/Gender
Female
Age
49 Years to 52 Years

Inclusion criteria

Inclusion criteria: 60 female volunteers; age between 49 and 52 years old; in menopause after one year of the last menstrual period

Exclusion criteria

Exclusion criteria: Patients with cardiorespiratory disorders; neurological; and other known impairments that prevent the subject from carrying out the procedures; do not drink alcoholic beverages; nor consume substances containing isoflavones such as green tea, peas, peanuts, chickpeas, lima beans, broad beans, lentils and flaxseeds; or carry out high-intensity training for 24 hours prior to the assessment

Design outcomes

Primary

MeasureTime frame
To evaluate the acute effect of isoflavones on the cardiovascular health of menopausal women, identifying linear and non-linear indices of frequency variability through evaluation in aerobic exercise using a polar cardiac monitor—

Secondary

MeasureTime frame
The acute use of isoflavones is expected to reduce common symptoms of menopause, being assessed using the Greene Climacteric Scale to assess somatic symptoms, as well as health-related quality of life, in addition to the Kupperman Index to measure somatic complaints (symptoms physical) recurrent during menopause; in addition to improving metabolic profile markers, such as glucose, total cholesterol and fractions and triglycerides, calcium, inorganic phosphorus, alkaline phosphatase and 25-OH vitamin D in menopausal women, which will be evaluated through biochemical evaluation carried out by trained professionals—

Countries

Brazil

Contacts

Public ContactAna Caroline Filipe

Fundação Universidade de Pernambuco

anacaroline.filipe@upe.br+55 (87) 38666468

Outcome results

None listed

Source: REBEC (via WHO ICTRP)