Effects of different types of physical exercise on functional capacity, pain, and cardiovascular health in breast cancer survivors

Umbrella project: effects of physical training approaches on functional status, pain, and cardiovascular health in breast cancer survivors

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

REBEC

Registry ID

RBR-7mf7rrp

Enrollment

Registered

2026-07-22

Start date

2026-05-29

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain

Interventions

This registration refers to an umbrella project composed of randomized clinical trials designed to investigate the effects of different physical exercise approaches in breast cancer survivors. The pro

Eligibility

Sex/Gender

Female

Age

30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Female breast cancer survivors; aged 30 to 70 years; diagnosis of stage I to III breast cancer; completion of primary cancer treatment, including surgery, chemotherapy and/or radiotherapy, at least three months before enrollment; no evidence of active disease at enrollment; medical clearance from the treating oncologist; medical clearance from the treating cardiologist

Exclusion criteria

Exclusion criteria: Breast cancer recurrence before enrollment; medical contraindication to physical exercise; absence of medical clearance from the treating oncologist or cardiologist; inability to understand or perform the study procedures; clinical conditions that preclude safe participation in the assessments or interventions

Design outcomes

Primary

Measure	Time frame
Improvement in cognition in breast cancer survivors is expected following different physical exercise approaches, determined by changes in Stroop Color and Word Test accuracy and response time, N-back task sensitivity index and response time, as well as task-evoked pupillary response measured by pupillometry, assessed before and after the interventions according to the design of each sub-study;Improvement in pain in breast cancer survivors is expected following different physical exercise approaches, determined by changes in pressure pain threshold and conditioned pain modulation, assessed before and after the interventions according to the design of each sub-study;Improvement in functional status in breast cancer survivors is expected following different physical exercise approaches, determined by changes in completion time in the standard, cognitive, and motor Timed Up and Go tests and dual-task cost, assessed before and after the interventions according to the design of each sub-study;Improvement in cardiovascular health in breast cancer survivors is expected following different physical exercise approaches, determined by changes in pulse wave velocity, augmentation index, blood pressure, heart rate, and heart rate variability, assessed before and after the interventions according to the design of each sub-study	—

Measure

Time frame

Improvement in cognition in breast cancer survivors is expected following different physical exercise approaches, determined by changes in Stroop Color and Word Test accuracy and response time, N-back task sensitivity index and response time, as well as task-evoked pupillary response measured by pupillometry, assessed before and after the interventions according to the design of each sub-study;Improvement in pain in breast cancer survivors is expected following different physical exercise approaches, determined by changes in pressure pain threshold and conditioned pain modulation, assessed before and after the interventions according to the design of each sub-study;Improvement in functional status in breast cancer survivors is expected following different physical exercise approaches, determined by changes in completion time in the standard, cognitive, and motor Timed Up and Go tests and dual-task cost, assessed before and after the interventions according to the design of each sub-study;Improvement in cardiovascular health in breast cancer survivors is expected following different physical exercise approaches, determined by changes in pulse wave velocity, augmentation index, blood pressure, heart rate, and heart rate variability, assessed before and after the interventions according to the design of each sub-study

—

Secondary

Measure	Time frame
No secondary outcome	—

Countries

Contacts

Public ContactDaniela Vitoria

Universidade Federal de Sergipe

danielacristina908@gmail.com+55(96)981273041

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Aug 10, 2026