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Effects of physical exercise on muscle control in people with Parkinson's disease

Bone health in Parkinson's Disease: relationship between aspects of bone fragility, mobility, balance and propensity to fall

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-7m8d7mp
Enrollment
Unknown
Registered
2021-06-01
Start date
2017-04-03
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's disease, Postural balance, Exercise therapy.

Interventions

After accepting the invitation to participate in the study and signing the Informed Consent Form (ICF), the participants underwent clinical evaluations, imaging exams, and biomechanical analyses. A gr
E02.760.169.063.500.387

Sponsors

Universidade Federal do Paraná - UFPR
Lead Sponsor
Pontifícia Universidade Católica do Paraná - PUCPR
Collaborator
Universidade Tecnológica Federal do Paraná - UTFPR
Collaborator

Eligibility

Age
60 Years to 100 Years

Inclusion criteria

Inclusion criteria: Aged 60 or older, both sexes, diagnosed with idiopathic Parkinson's Disease (IPD) by a neurologist specializing in Movement Disorders and in stages 1 to 3 on the Hoehn and Yahr scale.

Exclusion criteria

Exclusion criteria: Participants who presented cognitive deficits evaluated by means of the Mini Mental State Examination (MMSE) or adverse clinical conditions that could impede participation in the proposed protocol were excluded, as well as severe visual impairment, women in the post-menopausal phase, those using Deep Brain Stimulation (DBS), patients participating in some type of stretching activity, muscle strengthening or regular balance training, any motor sequelae that compromised balance and/or difficulty in locomotion, as well as patients restricted to a wheelchair (wheelchair). Osteometabolic diseases or the use of medications that interfere with bone metabolism, such as corticosteroids and bisphosphonates, were also excluded.

Design outcomes

Primary

MeasureTime frame
Outcome 1: strength and muscle power of flexors and extensors of the lower limbs were evaluated by isokinetic dynamometry (CYBEX®). Statistical analysis will show if there was, on average, a statistical difference between pre and post intervention by proposing a protocol of physical exercises to strengthen the quadriceps.

Secondary

MeasureTime frame
Outcome 2. Bone quality was evaluated by bone densitometry in the femoral neck and lumbar spine segments. The statistical analysis will verify whether the segments evaluated before and after the intervention suffered changes that, associated with the condition of muscle strength, interfere with the postural pattern.;Outcome 3. Timed up and go, an instrument that assessed physical mobility and tendency to fall. The statistical analysis will verify if a good motor control can influence the reduction of the risk of falling after the intervention. ;Outcome 4: Tinetti Index, an instrument composed of the Gait and Balance scales, which further addressed the issue of static and dynamic balance. Statistical analysis will verify if good motor control can influence balance control and better postural pattern after the intervention.

Countries

Brazil

Contacts

Public ContactLuciano Leandro
leandro.lal@hotmail.com55 41 3360-1800

Outcome results

None listed

Source: REBEC (via WHO ICTRP)