Intermittent Claudication
Conditions
Interventions
Randomized groups: control and training.
Control: Stretching, 2x/week, 30 min/day, 12 weeks
Training: Walking, 2x/week, 15 sets of 2 min exercise/2 min pause, intensity: heart rate of pain threshold,
other
F01.145.632
Sponsors
Escola de Educação Física e Esporte da Universidade de São Paulo
Ambulatório de Claudicação Intermitente do Hospital das Clínicas Faculdade de Medicina da Universidade de São Paulo
Programa de Promoção de Envelhecimento Saudável do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Eligibility
Sex/Gender
Male
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: Men Aged between 50 and 80 years Ankle-brachial index lower than 0.9 Peripheral artery disease - level II Able to walk on a treadmill for at least 2 min at 3.2 km/h Absence of obesity Systolic and diastolic blood pressures lower than 160 and 105 mmHg, respectively Absence of bypass surgery or angioplasty for at least one year Not using beta-blockers, non-dihydropyridine calcium channel antagonists or peripheral vasodilators Absence of leg amputation Absence of orthopedic problems that contraindicates walking.
Exclusion criteria
Exclusion criteria: Presence of complex arrhythmias and/or ischemia during exercise Fasting glycemia greater than 250mg/dl Presence of autonomic dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamics - evaluated by the measurement of blood pressure (auscultatory and ambulatory), cardiac output (CO2 rebreathing)and heart hate (ECG) performed before and after acute session (control or walking) and at the beginning and end of training. Systemic vascular resistance and stroke volume will be calculated.;Autonomic modulation - evaluated by the measurement of heart rate and blood pressure variabilities (spectral analysis) performed before and after acute session (control or walking) and at the beginning and end of training. ;Vascular function - evaluated by the measurement of baseline blood flow and its response to the reactive hyperemia maneuver (venous occlusion pletismography) performed before and after acute session (control or walking) and at the beginning and end of training. | — |
Secondary
| Measure | Time frame |
|---|---|
| Exercise capacity - evaluated by an maximal treadmill exercise test, achieving peak oxygen uptake, initial claudication distance, and total walking distance | — |
Countries
Brazil
Contacts
Public ContactCláudia ;Claudia Forjaz;Forjaz
Escola de Educação Física e Esporte da Universidade de São Paulo;Escola de Educação Física e Esporte da Universidade de São Paulo
Outcome results
None listed