Anesthesia, General. Intubation, Intratracheal
Conditions
Interventions
This is a prospective randomized clinical trial in adult patients undergoing general anesthesia with indication for orotracheal intubation. The eligible patient will proceed to randomization to the co
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Sponsors
Universidade Federal de São Paulo - UNIFESP/EPM
Hospital São Paulo - SPDM
Eligibility
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients indicated for elective surgical interventions under general anesthesia and tracheal intubation; both genders; age between 18 and 80 years; American Society of Anesthesiologists physical status classification ASA I or II
Exclusion criteria
Exclusion criteria: Emergency procedures; psychiatric disorders; suspected difficult airway; contraindication to manual ventilation under a face mask; use of beta-blockers; cardiac arrhythmia; use of opioids or other illicit drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate whether there is an additive anti-nociceptive effect to the drugs used in the induction of general anesthesia with 2% lidocaine solution without vasopressor administered prior to tracheal intubation. This assessment will be made using the NOL variation gradient (measured by the NOL Medasense monitor) pre and post intubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate whether there is a preferred route for administering 2% lidocaine solution without vasopressor - intravenous or laryngotracheal - in terms of reducing nociception associated with tracheal intubation. | — |
Countries
Brazil
Contacts
Public ContactSimone Abib
Universidade Federal de São Paulo - UNIFESP/EPM
Outcome results
None listed