Aortic Valve Stenosis
Conditions
Interventions
Group of 1200 patients diagnosed with severe Aortic Stenosis from the Instituto do Coração, Hospital das Clínicas, University of São Paulo, who underwent Aortic Valve Replacement Surgery between the p
V03.175.500
Sponsors
Hospital das Clínicas da Faculdade de Medicina da USP
Hospital das Clínicas da Faculdade de Medicina da USP
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Severe Aortic Stenosis undergoing valve replacement surgery; age over 18 years; male and female genders
Exclusion criteria
Exclusion criteria: Severe aortic insufficiency; severe primary valvular heart disease; heart failure of non-valvular etiology; primary cardiomyopathies; severe obstructive pulmonary disease; endocarditis; three-vessel coronary disease; main stem lesion; previous cardiac surgery;active endocarditis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Test whether the new stratification predicts the primary composite outcome: all-cause mortality and hospital readmission at 24 months of follow-up after conventional aortic valve replacement surgery in patients with severe aortic stenosis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Investigate whether there are other predictive factors for the composite outcome of all-cause mortality and in-hospital readmission during the same follow-up period.;Investigate the prevalence of isolated outcomes (death from all causes and hospital readmission) within the same follow-up period.;Test whether the new stratification predicts the secondary outcome of mortality from cardiovascular causes in the same follow-up period. | — |
Countries
Brazil
Contacts
Public ContactCristhian Romero
Instituto do Coração, Universidade de São Paulo, Brasil
Outcome results
None listed