obesity
Conditions
Interventions
Two arms intervention: one group received 50,000 IU/month of oral vitamin D supplementation (n = 27) and another group received 800 IU/day of oral vitamin D supplementation as an active control (n = 3
E02
VS2
Sponsors
Universidade Federal do Rio de Janeiro
Centro Multidisciplinar de Cirurgia Bariátrica e Metabólica
Eligibility
Age
20 Years to 59 Years
Inclusion criteria
Inclusion criteria: Patients who underwent bariatric surgery using Roux-en-Y gastric bypass (RYGB); BMI higher or equal to 35 kg/m2; aged between 20 and 60 years and serum biochemistry outcomes collected before their scheduled RYGB.
Exclusion criteria
Exclusion criteria: Previous bariatric, disabsortive or restrictive gastrointestinal surgeries; immunosuppressive therapy use; pregnant or planning a pregnancy in the next 6 months; lactation; smoking; cancer and intestinal disabsortive syndromes diagnosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum reduction in non-HDL cholesterol levels, assessed by biochemicals laboratory measurements, aiming to reduce at least 10% of this parameter after six months of intervention.;Serum reduction in thyroid-stimulating hormone (TSH) levels, assessed by biochemicals laboratory measurements, aiming to reduce at least 20% of this parameter after six months of intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum reduction in hepatic enzymes levels, assessed by biochemicals laboratory measurements, aiming to reduce at least 50% of this parameter after six months of intervention.;Serum reduction in neutrophil-to-lymphocyte ratio, assessed by biochemicals laboratory measurements, aiming to reduce at least 15% of this parameter after six months of intervention. | — |
Countries
Brazil
Contacts
Public ContactRoberta Carvalho
Outcome results
None listed