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Changes in body fat and muscle mass in overweight adolescents and genetic predisposition to obesity, submitted to different physical exercise programs

Body composition and Genetic assessments in Overweight adolescents and young people and Obese, submitted to different Physical Activity Programs

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-7hsjfjk
Enrollment
Unknown
Registered
2021-06-17
Start date
2017-08-07
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The study was conducted in healthy humans, high school scholars from state public schools, aged 15 to 19 years old, whose investigation was based on the diagnosis and monitoring of overweight and obesity. Adolescents characterized as overweight and obese were considered eligible and invited to participate in this clinical trial. Overweight, Obesity, Polymorphism Single Nucleotide, Adolescent

Interventions

In a preliminary stage, the diagnosis of the nutritional status of high school students from state public schools was determined, aged between 15 and 19 years in the municipality of Divinópolis, Minas
D017666

Sponsors

Universidade Federal de São João del Rei
Lead Sponsor
Universidade Federal de São João del Rei
Collaborator

Eligibility

Age
15 Years to 19 Years

Inclusion criteria

Inclusion criteria: Adolescents characterized as overweight and obese, aged between 15 to 19 years old, enrolled in the state public school system, in morning, afternoon or night shifts; agree to participate in the study, by presenting a Free and Informed Consent Form (TCLE) signed by parents and / or guardians (when minors) or by the volunteer (when over 18); underage individuals should sign the Informed Consent Form.

Exclusion criteria

Exclusion criteria: Unavailability to participate in evaluations or unable to attend School Physical Education classes; presentation of an injury picture (before or during the intervention program) that would permanently disable them to practice the exercises; maximum limit of 20% of consecutive absences in the intervention program; unavailability to participate in the stages of the study.

Design outcomes

Primary

MeasureTime frame
Expected outcome 1: Reduction of body fat, assessed using the deuterium oxide dilution method, in kilograms or Percentage relative to body weight. Data collected before the start of the exercise program, and 10 weeks after the intervention.;Outcome found 1: In participants with the rs9939609A polymorphism, practicing the aerobic program, significant reductions in body fat mass were caused.

Secondary

MeasureTime frame
Expected outcome 6: Reduction of fasting triglycerides, assessed using the colorimetric enzymatic method, in mg / dL. Data collected before the start of the exercise program, and 10 weeks after the intervention.;Outcome found 6: No significant changes were found in the fasting triglyceride levels of the participants, after the 10-week intervention program with different physical exercise programs.;Expected outcome 7: Reduction of fasting LDL-cholesterol, assessed by calculation using the Friedewald equation, in mg / dL. Data collected before the start of the exercise program, and 10 weeks after the intervention.;Outcome found 7: No significant changes were found in the participants' LDL-cholesterol levels after the 10-week intervention program with different physical exercise programs.;Expected outcome 8: Reduction of fasting VLDL-cholesterol, assessed by calculation using the Friedewald equation, in mg / dL. Data collected before the start of the exercise program, and 10 weeks after the intervention.;Outcome found 8: No significant changes were found in the participants' VLDL-cholesterol levels after the 10-week intervention program with different physical exercise programs.;Expected outcome 9: Increase in fasting HDL-cholesterol, assessed by selective precipitation of LDL and VLDL and finally by means of the colorimetric enzymatic method, in mg / dL. Data collected before the start of the exercise program, and 10 weeks after the intervention.;Outcome found 9: No significant changes were found in the participants' HDL-cholesterol levels after the 10-week intervention program with different physical exercise programs.;Expected outcome 10: Reduction of blood pressure at rest, assessed using an automatic blood pressure device, in mmHg. Data collected before the start of the exercise program, and 10 weeks after the intervention.;Outcome found 10: Significant reductions in resting systolic blood pressure were found in participants who did not have the rs9939609A bodybui

Countries

Brazil

Contacts

Public Contactwendell bila
wendellbila1@gmail.com+55-37-988456679

Outcome results

None listed

Source: REBEC (via WHO ICTRP)