Postoperative pain
Conditions
Interventions
We calculated a number of 50 participants, 25 in each group. We have increased to 30 participants in each group for compensation for possible losses. Participants will be electronically divided into t
Sponsors
Real e Benemérita Associação Portuguesa de Beneficência
Real e Benemérita Associação Portuguesa de Beneficência
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Patients scheduled for medium-sized gynecological surgical laparoscopy (hysterectomy, oophorectomy, salpingectomy, endometriosis, without intestinal involvement, without inflammatory disease); who freely agree to sign the consent form and participate in the study
Exclusion criteria
Exclusion criteria: Cases that evolve with serious surgical complications (organ damage, hemorrhage, etc.); widening of the interval between the Q and T waves on the electrocardiogram; heart block other than first-degree atrioventricular block; renal failure; alteration in neuromuscular function; chronic pain in treatment with corticosteroids and/or opioids; allergy/contraindication to any of the study components
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate postoperative analgesia after gynecological videolaparoscopy in patients receiving magnesium sulfate or methadone. It is expected to find superior analgesia in patients receiving methadone. The analyzed outcomes will be morphine consumption, postoperative pain scores (30 min after waking up, 6 h after waking up and on the 1st and 2nd PO day after 6 pm), brief pain inventory (pre and 6 h after awakening from anesthesia). Pain will be assessed according to a numerical pain scale (0 to 10, with 0 being no pain and 10 being the worst imaginable pain), explained to patients in the pre-anesthetic evaluation | — |
Secondary
| Measure | Time frame |
|---|---|
| Assess the incidence of nausea and vomiting, time between interruption of anesthesia and SetLine = 50, mini-mental state examination (pre and 3 h after surgery);Assess the incidence of nausea and vomiting, time between interruption of anesthesia and SetLine = 50, mini-mental state examination (pre and 3 h after surgery) | — |
Countries
Brazil
Contacts
Public ContactSebastião Silva Filho
Sociedade Portuguesa de Beneficência de Santos
Outcome results
None listed