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Antimicrobial action of cleaning methods for dentures of hospitalized patients

Antimicrobial effectiveness of denture cleaning protocols for hospitalized patients: randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-7gstxs6
Enrollment
Unknown
Registered
2022-03-25
Start date
2018-10-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hospitalization

Interventions

A total of 340 patients admitted to the ward of two hospitals in the city of Bauru and users of conventional removable upper complete dentures, regardless of age, sex, condition of the mandibular arch
Placebo Group 2: 20 patients admitted to a hospital ward who had their upper complete dentures submitted to a single brushing with a new soft brush and toothpaste for 2 minutes
Placebo Group 3: 20 patients admitted to a hospital ward who had their upper complete dentures submitted to a single brushing for 2 minutes with a new soft brush and 5 mL of neutral liquid hand soap
Experimental Group 1: 20 patients admitted to a hospital ward who had their upper complete dentures submitted to a single immersion in 150 mL of 0.12% chlorhexidine gluconate for 20 minutes
Experimental Group 2: 20 patients admitted to a hospital ward who had their upper complete dentures submitted to a single immersion in 150 mL of 2% chlorhexidine gluconate for 10 minutes
Experimental Group 3: 20

Sponsors

Karin Hermana Neppelenbroek
Lead Sponsor
Faculdade de Odontologia de Bauru - Universidade de São Paulo
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients in hospital ward; both sexes; over 18 years old; users of conventional removable upper complete; any condition of the mandibular arch; any level of consciousness; any reason for hospitalization.

Exclusion criteria

Exclusion criteria: Patients with fractured and/or relined upper complete dentures.

Design outcomes

Primary

MeasureTime frame
Determine the most effective hygiene protocol for reducing the biofilm present in upper complete dentures of hospitalized patients, by determining the area of coverage of prosthetic biofilm and the count of viable microbial colonies from the finding of a significant reduction in the percentage area of biofilm visible on the internal surface of the denture and the number of viable microorganisms (CFU/mL) in non-selective culture medium.

Secondary

MeasureTime frame
Secondly, the adoption of an easy, efficient, affordable, and applicable protocol in a hospital environment for the hygiene of removable acrylic dentures can result in shorter hospital stays for both the prevention of infections associated with the prosthetic biofilm and the reduction of the virulence course. of a previously installed lung disease, leading to lower hospitalization costs.

Countries

Brazil

Contacts

Public ContactKarin Neppelenbroek

Faculdade de Odontologia de Bauru - Universidade de São Paulo

khnepp@yahoo.com.br+55-014-32358245

Outcome results

None listed

Source: REBEC (via WHO ICTRP)