Occupational Stress, fatigue.
Conditions
Interventions
In total, 45 shift workers will be followed for 12 months to take dry extract of Rhodiola rosea - RRE (standardized to 2.0 - 4.0% rosavine) 400 mg / day or placebo in the morning. As this is a cross-o
Drug
Sponsors
Universidade Federal de Ouro Preto
Vale S A
Eligibility
Age
18 Years to 18 Years
Inclusion criteria
Inclusion criteria: Workers shortlisted for the high performance operator program according to the company's operational technical criteria will be included in the study
Exclusion criteria
Exclusion criteria: Operators who submit will be excluded: Evidence of substance abuse or dependence in the last 5 years. Non-medical psychiatric treatment at least 4 weeks before study. Clinically significant 24-hour Holter abnormality as complex ventricular arrhythmias, defined as sustained ventricular tachycardia, second-degree mobitz type II or more atrioventricular block, sinus pauses longer than 3 seconds, presence of more than 30 episodes of extrasystoles per hour, and atrial fibrillation or flutter Decompensated metabolic disorders such as diabetes with glycated hemoglobin (HbA1c) greater than 9% and dyslipidemia with LDL greater than 180 mg / dL or triglycerides greater than 500 mg / dL. Degenerative chronic diseases (autoimmune, neoplasia, immunodeficient disease and neurological diseases). Operators with signs and symptoms of infectious diseases. Gastrointestinal disorders with altered absorption. Carriers of moderate to severe sleep disorder Using the following medicines: amitriptyline, clomipramine, imipramine, nortriptyline, fluoxetine, sertraline, paroxetine, venlafaxine, citalopram, lithium carbonate, valproic acid, sodium divalproate, carbamazepine, risperidone, olanzapine, haloperidol, monoaminoxpride inhibitors, moclobemide or selegiline.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find a decrease in fatigue prevalence after the intervention verified by applying the "Multidimensional Fatigue Inventory 20 (MFI-20)" scale and numerical analog scales (NASs) of chronic fatigue symptoms before and after the experiment. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find increased quality of life after the intervention verified by applying the "World Health Organization Quality of Life-36 (WHOQOL-bref)" questionnaire before and after the experiment. | — |
Countries
Brazil
Contacts
Public ContactRaimundo do Nascimento Neto
Universidade Federal de Ouro Preto (UFOP)
Outcome results
None listed