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Comparison of the effects of oral and intramuscular use of corticosteroids on pain, swelling and mouth opening and closing movements after extraction of the wisdom tooth

Comparative study of the effectiveness of two routes of corticosteroid administration to control edema, trismus and pain after surgical extraction of impacted third molars

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-7g6qq8
Enrollment
Unknown
Registered
2019-03-25
Start date
2011-07-27
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Molar, Third

Interventions

Interventions: comparison of the use of different modes of administration of corticosteroids, oral (Control Group) and intramuscular (Intervention Group), in the extraction of third molars. The proced
Drug

Sponsors

Universidade Federal do Paraná
Lead Sponsor
Universidade Federal do Paraná
Collaborator

Eligibility

Age
16 Years to 35 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria were: healthy subjects, aged over 16 years of either sex, without contraindications for corticoid treatment, no history of pericoronitis for the last 6 months, no history of recent illness that required medications that could alter the inflammatory response, no use of medication that could interfere with the healing process and who required extraction of all four third molars. The extractions were all of similar technical difficulty and orthopantomography showed positioning and depth of impaction to be symmetrical in each arch. All patients required ostectomy and tooth sectioning of the lower third molar to achieve extraction. The difficulty was determined by means of the Pell and Gregory classification.

Exclusion criteria

Exclusion criteria: Occurrence of post-operative local infection Failure to attend second surgical procedure

Design outcomes

Primary

MeasureTime frame
Lower formation of swelling, trismus and pain after extraction of third molars from the side of the mouth in which the exodontia was made and intramuscular corticosteroid administration in relation to the side administered orally is expected. The method used to evaluate swelling and trismus was through the measurement of predetermined points, and to measure the pain a visual scale was used. From the observation of a variation in the pre- and post-intervention measurements, we can see if the outcome actually occurred.

Secondary

MeasureTime frame
It is expected to find differences between measures of swelling at different preoperative moments, 48 hours and 7 days after extraction. From the observation of a variation in the pre and post extraction measurements we can see if the outcome actually occurred.;It is expected to find differences between the measures of trismus in the different moments of preoperative, 48 hours and 7 days after extraction. From the observation of a variation in the pre and post extraction measurements we can see if the outcome actually occurred.;It is expected to find differences between the different measures of preoperative pain, 1 hour, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours, 24 hours, 36 hours, 48 hours, 60 hours, 72 hours and 84 hours after extraction. From the observation of a variation in the pre and post extraction measurements we can see if the outcome actually occurred.

Countries

Brazil

Contacts

Public ContactRafaela Scariot

Universidade Federal do Paraná

rafaela_scariot@yahoo.com.br+55 (41) 3360-4053

Outcome results

None listed

Source: REBEC (via WHO ICTRP)