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Analysis of Root Apex Healing and Postoperative Pain in Root Canal Treatment of Posterior Teeth with Apical Preparation Performed Using Different Instrument Diameters

Analysis of Periapical Healing and Postoperative Pain in Endodontic Treatment of Molar Teeth with Chronic Apical Periodontitis Using Different Apical Preparation Diameters: A Randomized Clinical Tria

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-7fhkrgz
Enrollment
Unknown
Registered
2025-11-04
Start date
2025-05-02
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic non-Suppurative Apical Periodontitis

Interventions

This is a randomized, controlled, two-arm, double-blind clinical trial. Experimental group: 43 patients diagnosed with chronic apical periodontitis will undergo endodontic treatment using the apical e

Sponsors

Faculdade de odontologia da universidade federal do amazonas
Lead Sponsor
universidade federal do amazonas
Collaborator

Eligibility

Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Adult competent patients between 18 and 65 years old; diagnosed with chronic apical periodontitis in molar teeth; who have a telephone for contact; and who agree to the terms of the study.

Exclusion criteria

Exclusion criteria: Pregnant patients; patients diagnosed with type I or type II diabetes; patients with hypersensitivity to anti-inflammatory drugs or analgesics; patients without a telephone for contact; patients with root alterations or dental conditions that prevent endodontic treatment; patients who, for any reason, cannot undergo single-session treatment.

Design outcomes

Primary

MeasureTime frame
To evaluate apical healing in endodontically treated teeth using the Periapical Index (PAI) (Ørstavik, Kerekes, & Eriksen, 1986) over a 12-month period

Secondary

MeasureTime frame
To evaluate the occurrence and intensity of postoperative pain at 12 h, 24 h, 48 h, and 72 h after endodontic treatment. ;To identify, through linear regression analysis, predictor variables that influence apical healing and postoperative pain.

Countries

Brazil

Contacts

Public ContactEduardo Nunes

Faculdade de odontologia da universidade federal do amazonas

fao@ufam.edu.br+55 92 33054924

Outcome results

None listed

Source: REBEC (via WHO ICTRP)