Anxiety
Conditions
Interventions
This is a randomized, double-blind, crossover clinical trial with two arms (theacrine and placebo). A total of 40 participants will be included, each undergoing two experimental sessions separated by
Sponsors
Universidade Federal do Rio de Janeiro Campus Macaé
Universidade Federal do Rio de Janeiro Campus Macaé
Eligibility
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Adults aged between 18 and 45 years; individuals engaged in resistance training for at least six months prior to the first study visit, to avoid delayed-onset muscle soreness typically observed in untrained individuals; with or without a diagnosis of common mental disorders (anxiety and/or depression); of both sexes
Exclusion criteria
Exclusion criteria: Osteoarthritis and rheumatoid arthritis; human immunodeficiency virus (HIV) infection; musculoskeletal disorders that prevent physical exercise; hypertension (systolic blood pressure above 120 mmHg and/or diastolic blood pressure above 80 mmHg); cardiovascular diseases; pregnancy and lactation; use of anticonvulsants; use of central nervous system stimulants, such as methylphenidate (Ritalin®, Concerta®), lisdexamfetamine (Vyvanse®, Juvene®), bupropion hydrochloride (Wellbutrin XL®, Zetron XL®, Bup), lithium carbonate (Carbolithium®); smokers, due to the stimulant effect of nicotine on the central nervous system. All information will be collected through anamnesis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected that taking theacrine at a dose of 200 mg after a single session may improve anxiety;It is expected that taking theacrine at a dose of 200 mg after a single session may improve mood;It is expected that taking theacrine at a dose of 200 mg after a single session may improve cognition;It is expected to reduce the perception of effort and during exercise caused by theacrine | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected that taking theacrine in a single dose of 200 mg after a single session may improve heart rate variability;It is expected that taking theacrine in a single dose of 200 mg after a single session may improve blood glucose and lactate;It is expected that ingestion of theacrine in a single dose of 200 mg after a single session may improve exercise tolerance and preference | — |
Countries
Brazil
Contacts
Public ContactGustavo de Oliveira
Universidade Federal do Rio de Janeiro Campus Macaé
Outcome results
None listed