Palatine Tonsil, Adenoids Hypertrophy
Conditions
Interventions
This is a randomized controlled clinical study with two arms. Children undergoing adenotonsillectomy will be randomly allocated in a one-to-one ratio through simple randomization using random number g
however, data analysis will be conducted by evaluators blinded to group allocation, following the intention-to-treat principle
Sponsors
Centro Integrado de Saúde Amaury de Medeiros - CISAM/UPE
Universidade de Pernambuco - UPE
Eligibility
Age
5 Years to 10 Years
Inclusion criteria
Inclusion criteria: Children of both sexes; age between five and ten years; confirmed medical indication for adenotonsillectomy due to obstructive sleep apnea, recurrent upper airway infections or other conditions associated with hypertrophy of the tonsils and adenoids, including mouth breathing syndrome; nutritional status classified as eutrophic, mild undernutrition or overweight according to body mass index for age expressed as Z score; preserved functional capacity; respiratory function within normal parameters for age, except for alterations related to tonsil and adenoid hypertrophy; legal guardians committed to adherence to the intervention protocol and participation in follow-up assessments; written informed consent signed by legal guardians
Exclusion criteria
Exclusion criteria: Hemodynamic instability; presence of chronic respiratory diseases in exacerbation, including asthma, cystic fibrosis or chronic bronchitis; acute respiratory infection within thirty days prior to the intervention, including pneumonia or bronchiolitis; congenital or acquired heart diseases; metabolic disorders such as type one or type two diabetes mellitus and hypothyroidism; regular use of corticosteroids or continuous use of bronchodilator medication; severe undernutrition or morbid obesity; previous specific nutritional follow-up; occurrence of severe complications during or after adenotonsillectomy, including hemorrhage or severe infections; need for surgical reintervention or prolonged mechanical ventilation; absence of informed consent from legal guardians
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in postoperative diaphragmatic function is expected, assessed by diaphragmatic ultrasonography, considering an increase in diaphragmatic excursion, an increase in diaphragm thickness, and improved contraction and relaxation velocity of the diaphragm, comparing the preoperative period with five, ten, and thirty days after surgery. As additional primary outcomes, improvement in functional performance assessed by the Three-Minute Step Test, improvement in body composition assessed by changes in mid-upper arm muscle circumference, triceps skinfold thickness, and estimated body fat percentage, as well as improvement in nutritional status assessed by the anthropometric parameters weight-for-age, height-for-age, and body mass index-for-age are expected | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in dietary intake is expected, assessed by means of the Food Frequency Questionnaire, with improvement in dietary intake markers and overall diet quality, as well as a positive association between dietary intake and postoperative recovery, evaluating the impact of diet on functional recovery | — |
Countries
BR
Contacts
Public ContactArianny de Sá
Universidade de Pernambuco - UPE
Outcome results
None listed