Autism
Conditions
Interventions
This was a two-arm, double-blind, randomized controlled clinical trial that initially included 24 children, of which only 17 participants completed the study, with 9 participants allocated to the expe
Sponsors
Universidade Federal do Amazonas
Universidade Federal do Amazonas
Eligibility
Age
2 Years to 3 Years
Inclusion criteria
Inclusion criteria: Clinical diagnosis of Autism Spectrum Disorder (ASD) confirmed by the Modified Checklist for Autism in Toddlers (M-CHAT) and a medical referral for speech-language therapy; symptomatic severity of ASD classified as Level I or II of support, based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5); both sexes; normal hearing, as confirmed by a Brainstem Auditory Evoked Potential (BAEP) test; age range from 2 to 3.5 years; not receiving any other concurrent multidisciplinary therapies alongside the research; absence of a cardiac pacemaker, metallic or electronic implant in the body; absence of epilepsy or seizure disorders; absence of other additional disorders or pathologies, such as Down syndrome, Cerebral Palsy, confirmed genetic syndromes, West syndrome, among others
Exclusion criteria
Exclusion criteria: Refusal of the responsible party to sign the informed consent form; low participant tolerance to the intervention, participant refusal of Transcranial Direct Current Stimulation (tDCS) or linguistic-motor therapy; having an interval greater than 3 consecutive days without intervention or 4 staggered days
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| It is expected to see better Bayley scale evaluative scores after 10 days of intervention;It is expected to see better scores on the (PROC) behavior observation protocol after 10 days of intervention | — |
Primary
| Measure | Time frame |
|---|---|
| It is expected that transcranial anodal direct current stimulation (tDCS) in the primary motor area associated with dual-task activities (linguistic-motor) will positively influence the acquisition of language skills for children with autism (ASD), after 10 days of stimulation;t is expected that participants demonstrate improved performance in expressive and receptive language following the sessions, thereby serving as a foundation for developing new therapeutic approaches for children on the autism spectrum. If it is confirmed that neuromodulation (electrical head stimulation) contributes to enhanced speech when combined with a dual-task of speech and gait, this will represent a significant advancement in the clinical field, offering the possibility of adopting this therapeutic strategy to improve the development of children with autism | — |
Countries
Brazil
Contacts
Public ContactJorciane Soares
Universidade Federal do Amazonas
Outcome results
None listed