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Comparison between ventilation with a pressure and with two positive pressure in the nostrils of premature newborns

Comparison of nasal CPAP and nasal CPAP with a Cycling Time in preterm infants

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-7d9dth
Enrollment
Unknown
Registered
2015-02-19
Start date
2010-11-17
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory distress syndrome, Noninvasive Ventilation, newborn

Interventions

Experimental group: 40 preterm infants on nasal CPAP with the cycling time (20 RN remained for a period of 48 hours in support and 20 RN remained for 72 hours). Control group: 40 preterm infants on na
Other

Sponsors

Universidade de Franca
Lead Sponsor
Santa Casa de Misericórdia de Franca
Collaborator

Eligibility

Age
24 Weeks to 35 Weeks

Inclusion criteria

Inclusion criteria: Infants born at a gestational age of less than 37 weeks and weighing less than 2,500g, who received noninvasive ventilation.

Exclusion criteria

Exclusion criteria: Newborns with congenital malformations, abdominal post-surgery and neonatal infection as well as term newborns

Design outcomes

Primary

MeasureTime frame
Compare ventilatory failure of premature newborns in nasal CPAP and nasal CPAP time cycled. Through observation was verified complications that prevented the continuation of the pressure support resulting in the failure.;It has been found fault in pressure support of 62.5% (25 infants) in nasal CPAP group and 30% (12 newborns) in CPAP time cycled, indicating association of noninvasive ventilation failure in CPAP (p <0 05, OR 1.22).

Secondary

MeasureTime frame
Register the causes of the occurrence of the failure of newborns in non-invasive support. ;The Apnea was the main cause for the occurrence of the failure of newborns in the noninvasive pressure support, with 32.5% highlighting the CPAP group.

Countries

Brazil

Contacts

Public ContactCarmem;Marisa Silveira;Brunherotti

Santa Casa de Misericórdia de Franca;Universidade de Franca

cstsilveira@gmail.com;brunherotti@uol.com.br+55(16)37241125;+55(16)8112-7768

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 22, 2026