Chondromalacia Patellae
Conditions
Interventions
The entire randomization process will be conducted using the application (Randomizer for Clinic® MEDSHARING, version 1.4) and will be overseen by an administrative technician who will have no affiliat
Sponsors
Universidade Comunitária de Região de Chapecó
Universidade Comunitária de Região de Chapecó
Eligibility
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Participants of both genders. Aged between 18 and 45 years. With a clinical diagnosis of patellar chondromalacia (grades I, II, III, and IV according to the classification of the International Cartilage Repair Society - ICRS)
Exclusion criteria
Exclusion criteria: Participants who have undergone recent surgical procedures (in the last three months). Peripheral vascular disease diagnosis. Diagnosis of hypertension. History of deep vein thrombosis or pulmonary embolism. Currently on anticoagulants. Previous history of myocardial infarction or prior stroke. Currently using type II collagen or chondroprotective agents. Patients who report knee joint injections in the last six months. Those with any type of gait alteration or difficulty. Lower limb deformity or axis deviation. Ligamentous or meniscal injuries
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the patellar cartilage thickness through images obtained from magnetic resonance imaging (MRI) of the knee joint at the beginning and end of the study. Preservation or an increase in cartilage thickness is expected following the intervention protocols.;The expectation is to observe an approximately 5% increase in blood concentrations of CTX-II at the conclusion of the interventions.;reduction in pain associated with chondromalacia patella (assessed by the visual analogue scale) of more than 30% is expected among patients after the interventions. | — |
Secondary
| Measure | Time frame |
|---|---|
| Maximum dynamic strength, assessed by the one repetition maximum test (1-RM), proposed by Brown and Weir (2001), should increase by around 50% in response to the proposed interventions.;Improvements in the perception of quality of life (greater than 5%), assessed by the Lequesne questionnaire (2006), considering pain, gait and joint stiffness are expected. | — |
Countries
Brazil
Contacts
Public ContactClodoaldo De Sá
Universidade Comunitária de Região de Chapecó
Outcome results
None listed