Epidural Anesthesia
Conditions
Interventions
In group 1 (epidural combined with general anesthesia, n = 30), with the patients in a seated position, epidural block was performed with 18G Tuohy needle after local anesthesia provided with 60 mg of
(ii) propofol (2.0 to 2.5 mg.kg-1) followed by rocuronium (0.6 mg.kg-1) for intubation, injected within 5 seconds. The patients were ventilated under mask with 100% oxygen, until the maneuvers of lary
Drug
Device
Procedure/surgery
Sponsors
Faculdade de Ciências Médicas - Universidade Estadual de Campinas
Faculdade de Ciências Médicas - Universidade Estadual de Campinas
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Elective Abdominal Surgeries performed under general anesthesia with or without association of epidural analgesia; female sex; age between 18 and 65 years old. Use of neuromuscular blocking agents; physical state ASA 1 and 2.
Exclusion criteria
Exclusion criteria: neuromuscular, renal and hepatic diseases; BMI greater than 32.5 or less than 20.0 kg.m-2; hydroelectrolytic and acid-base disorders; use of drugs that interact with neuromuscular blockers; contraindication to spinal blocks; history of hypersensitivity to drugs used
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Predicted outcome: A 20% time extension for recovery of a T4 / T1 ratio of 90% TOF = 0.9, assessed by monitoring neuromuscular block through peripheral nerve stimulator and thumb accelerometer measurement continuously evaluated throughout the operation, only after the intervention.; Outcome found: there was no prolongation in time for recovery of a T4 / T1 ratio of 90% TOF = 0.9. | — |
Secondary
| Measure | Time frame |
|---|---|
| Predicted outcome: A 20% time extension for the clinical duration, assessed by monitoring neuromuscular block through peripheral nerve stimulator and thumb accelerometer measurement continuously evaluated throughout the operation, only after the intervention.;Outcome found: there was no prolongation in clinical duration. | — |
Countries
Brazil
Contacts
Public ContactFernando Eduardo Junqueira
Faculdade de Ciências Médicas - Universidade Estadual de Campinas
Outcome results
None listed