Comparison of the use of different volumes of Nasal Irrigation Solution in postoperative period of Nasal Endoscopic Surgery in patients with Chronic Sinusitis with Nasal Polyps

Comparison of the use of different volumes of Saline Solution with Corticosteroids in postoperative period of Nasal Endoscopic Surgery in patients with Chronic Rhinosinusitis with Nasal Polyps

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

REBEC

Registry ID

RBR-7ctn7pp

Enrollment

Unknown

Registered

2023-11-03

Start date

2022-11-01

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sinusitis

Interventions

This is a two-arm, single-blinded, randomized controlled clinical study. A total of 40 people meeting the eligibility criteria will be allocated to one or another intervention group using manual rando

E02.319.267.120.655.500

Eligibility

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: We will evaluate patients in the immediate postoperative period of nasal endoscopic surgery due to Chronic Rhinossinusitis with Nasal Polyps. Patients aged 18 to 70 years who have bilateral disease and who have undergone at least anterior and posterior ethmoidectomy and bilateral maxillary antrostomy will be included

Exclusion criteria

Exclusion criteria: Patients with suspected systemic diseases with nasal involvement, such as cystic fibrosis and ciliary dyskinesia. Patients with exacerbations at the time of the surgical procedure

Design outcomes

Primary

Measure	Time frame
To evaluate symptomatic improvement, using the SNOT-22 questionnaire, and nasal endoscopy parameters, using the Lund-Kennedy score, 30 and 60 days after the surgical procedure, and compare the results between the two groups	—

Secondary

Measure	Time frame
No secondary outcomes are expected	—

Countries

Brazil

Contacts

Public ContactIsabella Freitas

Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo

isabella.bezerra17@gmail.com+55 (016) 3315-3001

Outcome results

None listed

Source: REBEC (via WHO ICTRP)