Obstructive Sleep Apnea Syndrome
Conditions
Interventions
Two interventions were carried out:
1. Cardiopulmonary Exercise Test
The Cardiopulmonary Exercise Testing was performed on a cycle ergometer electromagnetic braking using Inbras port CG-04 (Inbraspo
Moreover, the FC is continuously measured by the pulse wave read by the oximeter, as well as electrodes C3, D1, D2 mentonianos were affixed to de
Other
Sponsors
Universidade Federal da Paraíba
Pulmonar Diagnóstico
Eligibility
Age
60 Years to 100 Years
Inclusion criteria
Inclusion criteria: Aged 60 years or older; Men and women; body mass index (BMI) between 18.5 and 29.9 kg / m²; Diagnosed with hypertension; No use of beta-blockers; Considered irregularly active (IPAQ adapted for the elderly).
Exclusion criteria
Exclusion criteria: Smokers / recent ex-smokers (<6 months); Diabetes mellitus; restrictive respiratory diseases / obstructive and / or cardiovascular
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiorespiratory response was considered our primary outcome. For its evaluation was performed Cardiopulmonary Exercise Test. Participants were instructed to eat light foods usually up to 2 hours prior to CPET, instructed to continue taking the medication in doses and usual hours, avoid physical activities and refrain from drinking alcohol or stimulating foods (with caffeine) 24 hours before testing. It was also requested that used comfortable clothes and shoes suitable for movement on the exercise bike. Before the test, the volunteers remained seated on the bike for about two minutes for evaluation and record blood pressure at rest through period auscultation technique which also received guidelines on cardiopulmonary exercise testing. The technical procedures followed the guidelines of the American Thoracic Society / American College of Chest Physicians for testing in cycle ergometers. Briefly, each patient underwent sitting at home a peripheral saturation recording (SpO2), electrocardiogram (ECG) and blood pressure and then started the ramp protocol in cycle ergometer (CG-04, Inbrasport, Porto Alegre, Brazil) with a rate of increase of constant load, starting without charge and 5-12 W / min increase rate up to the maximum tolerance limit (determined by the inability to continue pedaling frequency of pedaling 60 rpm). Subjects were encouraged through verbal stimuli to a test succeeded length between 8 and 12 minutes where every 2 minutes was recorded PA, ECG and SpO2. After the effort, the patients were monitored for 3 minutes pedaling without charge. The results of the cardiopulmonary stress test are shown in Table 1 (attached). In it, we see that both groups performed the exercise protocol with a similar workload (SAH: 78 (66-96) W / min; SAH + OSA: 85 (47-114) W / min, p> 0 , 05). Still, the cardiorespiratory variables and systolic blood pressure (SBP) were similar in both the groups (p> 0.05). On the other hand, SAH group + OSA had lower FCrec2 in relation to | — |
Secondary
| Measure | Time frame |
|---|---|
| The quality of sleep was the secondary endpoint of this study, assessed by polysomnography. All participants underwent an examination portable polysomnography and the diagnosis of the presence or absence of OSAS was performed and laudado by medical sleep specialist. The presence of OSAS was confirmed by the IAH. The survey was conducted during a full night in the participant's residence in spontaneous sleep and without sedation. Monitoring of variables was performed using a portable breathing monitor Embletta type (Embla, Embletta® Gold, USA), previously validated, as well as instruction on its operation. The Embletta monitor is able to continuously monitor the pulse oximetry to detect respiratory efforts (plethysmographic strap thoracoabdominal), measuring the airflow (this pressure sensor nasal cannula pressure) and record snores; Moreover, the FC is continuously measured by the pulse wave read by the oximeter, as well as electrodes C3, D1, D2 mentonianos were affixed to detect brain and muscle activity. The DSatO2 event was defined as the amount of reduction in SaO2 4% / h. As can be seen in Table 2 (attached), the SAH + OSA group had higher AHI values(SAH: 2.0 (0.8 to 3.3) events / h; SAH + OSA: 22.9 (17 , 9 to 27.5) events / h, p = 0.02) and DSatO2 (SAH: 1.7 (0.9 to 4.3) events / h; SAH+ OSAS: 11.5 (2.9 - 21.6) events / h, p = 0.02) when compared to the SAH group. There were significant differences in sleep architecture, characterized by a total time of greater sleep in OSAS + SAH group in relation to the SAH group (p <0.05). | — |
Countries
Brazil
Contacts
Public ContactBruno Barbosa
Universidade Federal da Paraíba
Outcome results
None listed