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Radiotherapy dose mapping for head and neck Cancer associated with treatment toxicities

Determination of dosimetric map from Intensity-modulated Radiotherapy for head and neck cancer and risk of associated toxicities

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-7cggk36
Enrollment
Unknown
Registered
2025-06-26
Start date
2022-01-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and Neck Neoplasms

Interventions

120 patients will be selected patients diagnosed with Cancer of head and neck, understanding to the locations C01 the C06, C09, C10, C11 and C30 to C32 and which will carry out treatment curative radi
V03.175.500

Sponsors

Santa Casa de Misericórdia da Bahia
Lead Sponsor
Universidade Federal da Bahia (UFBA)
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with head and neck cancer that are expected to receive 50-70 Gy in the primary radiation field with a classic fractionation scheme into daily doses of 2-2.12 Gy (sessions held from Monday to Friday, with breaks on weekends) and curative intent, totaling 5 to 7 weeks of treatment; patients must have completed oral adaptation aimed at eliminating foci of dental infection; aged 18 years or older; of both sexes

Exclusion criteria

Exclusion criteria: Patients who do not receive a radiotherapy dose between 50-70Gy, non squamous cell cancer diagnosis, patients who, for some reason, are unable to complete the planned dental adjustment; or who do not meet the other inclusion criteria described; patients who do not sign the Informed Consent Form or who express a desire to be excluded from the study will also be excluded

Design outcomes

Primary

MeasureTime frame
Create a dosimetric map of cervicofacial structures by calculating the estimated dose of radiotherapy for anatomical subtypes of head and neck cancer; ;Characterize the impact of radiation dose and distribution on the development of oral toxicities in patients with head and neck squamous cancer.

Secondary

MeasureTime frame
Contribute to the development of guidelines for standardizing organs at risk in head and neck tumors;Contribute to the development of a clinical guide of risk zone areas for typical dental procedures after head and neck radiotherapy

Countries

Brazil

Contacts

Public ContactLuciana Ramalho

Universidade Federal da Bahia (UFBA)

lucianapramalho2017@gmail.com+55(71) 3283-9023

Outcome results

None listed

Source: REBEC (via WHO ICTRP)