Alzheimer Disease
Conditions
Interventions
This is a cross-sectional clinical study in collaboration between the Faculty of Dentistry of Piracicaba and the Faculty of Dentistry of the University of Buenos Aires in which 36 volunteers aged betw
in the first stage of the study, volunteers will have their old prostheses evaluated according to Vigild's criteria (1987) to be classified as satisfactory or unsatisfactory according to their conditi
Volunteers will also be subjected to the Mini Mental State Examination to correlate the values ??with oral stereognosis (ability to understand the shape in the mouth) which will be assessed using six
(2) Before installing the new prostheses, with the volunteers without any prostheses
(3) Immediately after insertion of the new prostheses
(4) After the adaptation period for the new prosthesis, the volunteer is free from any discomfort
(5) After 3 months of using the new prostheses, counting from the period in which the volunteer is adapted to the new prostheses (no more complaints)
E07.695.190.200.205
Sponsors
Faculdade de Odontologia de Piracicaba - FOP/UNICAMP
Facultad de Odontología - FOUBA
Eligibility
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: Present good general health status or presence of controlled systemic diseases assessed during the anamnesis; be completely edentulous and have unsatisfactory complete dentures according to the Vigild criteria; be between 65 and 80 years old; and normal salivary flow of 0.6 ml/min or more. Patients in the experimental group must meet the criteria mentioned above and have a confirmed diagnosis of mild Alzheimer's disease by a neurologist using the International Classification of Diseases (ICD-10); Diagnostic and Statistical Manual of Mental Disorders (DSM-IV); Mini Mental State Examination (MMSE); and Clinical Dementia Rating (CDR) with a score of 1.0 or less
Exclusion criteria
Exclusion criteria: Participants with oral lesions; neuromuscular diseases; facial malformations; bruxism (with the presence of an edentulous tongue) and smokers (due to reduced salivary flow) will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find a difference in oral sensory capacity in individuals with mild Alzheimer's disease, compared to individuals with normal cognitive function, verified through the oral stereognosis test, in which a 3-point scale will be used to classify the answers as correct (2 points), partially correct (incorrect, but a form considered similar to the one presented was identified; 1 point), and incorrect (0 points). Thus, higher scores will indicate greater oral sensory capacity of the individual.;It is expected that prosthetic rehabilitation will promote improvements in the oral perception of volunteers with mild Alzheimer's disease and normal cognition, verified through the oral stereognosis test, in which higher scores will indicate greater oral sensory capacity of the individual, in addition to considering the time needed to identify each geometric shape. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcomes are expected. | — |
Countries
Argentina, Brazil
Contacts
Public ContactHeloísa Brandão
Faculdade de Odontologia de Piracicaba - FOP/UNICAMP
Outcome results
None listed