Spinal Cord Injuries
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: During a period of 10 to 12 months, we will select males; non-smokers; with traumatic SCI; with complete motor injury (ASIA A or B), between T4 and C5 levels; injured for more than 6 months; who are able to perform an arm crank exercise test in an upper limbs cyclergometer. They will be admitted from Neurorehabilitation in spinal cord injury program from Sarah Network of Rehabilitation Hospitals Brasília.
Exclusion criteria
Exclusion criteria: Will not be included in the study patients with scheduled surgery; with known heart or lung diseases; athletes; or who presents acute infectious syndromes or with any clinical decompensation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected an increase of 10% in peak oxygen uptake (VO2), after 4 weeks of inspiratory muscle training, measured on a maximal arm crank cardiopulmonary exercise test, compared to the control group. | — |
Secondary
| Measure | Time frame |
|---|---|
| All variables will be measured at baseline and after a four week training period. - Lung function: it is expected an improvement in vital capacity and in maximal inspiratory pressure in training group. Spirometry and manuvaccuometry test will measure: slow (VC) and forced vital capacity (FVC); Forced expiratory volume in 1 second (FEV1); FEV1/FVC and FEV1/CV relations; maximum expiratory and inspiratory pressures; nasal inspiratory pressure to sniff. - Exercise responses: it is expected an improvement in ventilatory efficiency and a higher ventilatory threshold, in comparison to control group. Other variables from cardiopulmonary exercise test: heart rate, systolic and diastolic blood pressure; carbon dioxide production (VCO2), minute ventilation (VE); ventilatory equivalent for O2 and CO2, VE/VCO2 slope; workload (W); respiratory quotient; oxygen pulse; peripheral O2 saturation; expired O2 and CO2 pressure; subjective percieved effort (0 to 10). - It is expected diaphragmatic thickening with training, that will be evaluated with conventional ultrassound. - Echocardiogram: significant changes in myocardial morphology or function like chambers' diameters and walls thickness, ejection fraction and cardiac output, are not expected. They will confirm lack of cardiac remodeling with this training modality. | — |
Countries
Brazil
Contacts
Rede Sarah de Hospitais de Reabilitação