Skip to content

Training respiratory muscles really improves functional capacity in patients with spinal cord injury?

Effects of Inspiratory Muscle Training with Dynamic Resistance on Aerobic Capacity in Traumatic Spinal Cord Injury: Randomized Controlled Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-7b399d
Enrollment
Unknown
Registered
2016-10-27
Start date
2017-01-03
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal Cord Injuries

Interventions

Inspiratory muscle training with dynamic resistance. In the training group: 100 breaths, using all the vital capacity and visual feedback, initially with 40% of the maximal inspiratory pressure measur
Other
E02.779.483
E02.779.483.875
E02.190.525.186

Sponsors

Rede Sarah de Hospitais de Reabilitação
Lead Sponsor
Rede Sarah de Hospitais de Reabilitação
Collaborator

Eligibility

Sex/Gender
Male
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: During a period of 10 to 12 months, we will select males; non-smokers; with traumatic SCI; with complete motor injury (ASIA A or B), between T4 and C5 levels; injured for more than 6 months; who are able to perform an arm crank exercise test in an upper limbs cyclergometer. They will be admitted from Neurorehabilitation in spinal cord injury program from Sarah Network of Rehabilitation Hospitals Brasília.

Exclusion criteria

Exclusion criteria: Will not be included in the study patients with scheduled surgery; with known heart or lung diseases; athletes; or who presents acute infectious syndromes or with any clinical decompensation.

Design outcomes

Primary

MeasureTime frame
It is expected an increase of 10% in peak oxygen uptake (VO2), after 4 weeks of inspiratory muscle training, measured on a maximal arm crank cardiopulmonary exercise test, compared to the control group.

Secondary

MeasureTime frame
All variables will be measured at baseline and after a four week training period. - Lung function: it is expected an improvement in vital capacity and in maximal inspiratory pressure in training group. Spirometry and manuvaccuometry test will measure: slow (VC) and forced vital capacity (FVC); Forced expiratory volume in 1 second (FEV1); FEV1/FVC and FEV1/CV relations; maximum expiratory and inspiratory pressures; nasal inspiratory pressure to sniff. - Exercise responses: it is expected an improvement in ventilatory efficiency and a higher ventilatory threshold, in comparison to control group. Other variables from cardiopulmonary exercise test: heart rate, systolic and diastolic blood pressure; carbon dioxide production (VCO2), minute ventilation (VE); ventilatory equivalent for O2 and CO2, VE/VCO2 slope; workload (W); respiratory quotient; oxygen pulse; peripheral O2 saturation; expired O2 and CO2 pressure; subjective percieved effort (0 to 10). - It is expected diaphragmatic thickening with training, that will be evaluated with conventional ultrassound. - Echocardiogram: significant changes in myocardial morphology or function like chambers' diameters and walls thickness, ejection fraction and cardiac output, are not expected. They will confirm lack of cardiac remodeling with this training modality.

Countries

Brazil

Contacts

Public ContactSergio Henrique Ramalho

Rede Sarah de Hospitais de Reabilitação

shrramalho@gmail.com+556133191698

Outcome results

None listed

Source: REBEC (via WHO ICTRP)