Pain, unspecified
Conditions
Interventions
The present study was a randomized, crossover, split-mouth, triple-blind clinical trial conducted in two sessions. A total of 41 volunteers were recruited, all of whom served as their own controls. Tw
E03.155.086.231
Sponsors
Faculdade de Odontologia de Piracicaba- Universidade Estadual de Campinas
Faculdade de Odontologia de Piracicaba- Universidade Estadual de Campinas
Eligibility
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Only healthy participants; both genders; aged between 18 and 40 years will be included; provided they have prior experience with local anesthesia; no history of complications from local anesthesia; and have intact maxillary canines that are responsive to electrical stimulation using a "Pulp Tester"
Exclusion criteria
Exclusion criteria: Pregnant or lactating women; volunteers with systemic conditions that contraindicate anesthesia; those with a history of allergic reactions to any components of the anesthetic solutions used; and those with inflammatory conditions in the region will not be included in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The study aims to demonstrate the anesthetic efficacy of two solutions in vestibular infiltration in the maxilla (supraperiosteal injection at the apex of the canine). Solution 1 (test): 1% Articaine Hydrochloride buffered with 1:400,000 Epinephrine, and Solution 2 (control): 4% Articaine Hydrochloride with 1:200,000 Epinephrine. The study expects to reduce injection pain and burning sensation, anesthetic latency time, and the duration of pulpal and soft tissue anesthesia | — |
Secondary
| Measure | Time frame |
|---|---|
| The study aims to compare the pH levels of the anesthetic solutions under investigation. | — |
Countries
Brazil
Contacts
Public ContactSidney Raimundo
Faculdade de Odontologia de Piracicaba- Universidade Estadual de Campinas
Outcome results
None listed