Skip to content

Effect of Water with Ozone in the treatment of Pericoronitis

Effect of Ozonated Water as an adjunct in the treatment of Pericoronitis: randomized controlled clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-79pss6w
Enrollment
Unknown
Registered
2024-11-22
Start date
2025-01-10
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pericoronitis

Interventions

The study will be a randomized, controlled, double-blind clinical trial, with up to 30 days of follow-up, carried out on patients with lower third molar pericoronaritis. The sample will consist of par
(2) distal wedge surgery when there is space for teeth to erupt with excess gingiva in the distal area and (3) follow-up for cases in which there is eruption without excess gingiva in the distal area.

Sponsors

Universidade Federal dos Vales do Jequitinhonha e MucurI
Lead Sponsor
Universidade Federal dos Vales do Jequitinhonha e MucurI
Collaborator

Eligibility

Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Participants with signs/symptoms of pericoronaritis, such as the occurrence of spontaneous pain, erythema, purulent or draining edema, affecting the gingiva of the oral cavity, located over the lower third molar; age 18 to 35 years; both sexes; surgical risk level I and level II, according to the American Society of Anesthesiologists (ASA I and ASA II); periodontal status level I and II, according to the American Academy of Periodontology; consent to participate in this clinical trial by signing the Informed Consent Form (ICF)

Exclusion criteria

Exclusion criteria: Participants with surgical risk level III and level IV, according to the American Society of Anesthesiologists (ASA III and ASA IV); with periodontal status level IV, according to the American Academy of Periodontology; undergoing antibiotic therapy in the last two months; with any medical contraindication for periodontal probing; currently using tobacco and aged less than 18 years and more than 35 years

Design outcomes

Primary

MeasureTime frame
We expect to find a difference in the level of pain and quality of life

Secondary

MeasureTime frame
A reduction in probing depth and recovery of the bone crest level in the distal second molar, greater mouth opening and less edema/erythema measured by the diameter of the lesion are expected

Countries

Brazil

Contacts

Public ContactJosé Ramos Glória

Universidade Federal dos Vales do Jequitinhonha e MucurI

jose.cristiano@ufvjm.edu.br+55(38)35326082

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 4, 2026