Polycystic Ovary Syndrome
Conditions
Interventions
120 women with polycystic ovary syndrome (PCOS) will be placed randomly in three parallel groups with a ratio of 1:1:2. Group I: 30 PCOS women will perform continuous aerobic physical training in a tr
Other
C04.182.612.765
E02.779.483
Q50.040
Sponsors
Faculdade de Medicina de Ribeirão Preto
Faculdade de Medicina de Ribeirão Preto
Eligibility
Sex/Gender
Female
Age
18 Years to 39 Years
Inclusion criteria
Inclusion criteria: Volunteers with PCOS between 18 to 39 years old; body mass Index between 18 and 39.9 kg/m2 (normal overweight and obesity grades I and II); Do not practice regular physical activity.
Exclusion criteria
Exclusion criteria: Presence of systemic disease that contraindicate to physical activity; presence of disabling musculo-skeletal disorders; use of drugs that interfere with the hypothalamic-pituitary-ovarian-axis and hormonal contraceptives; smoking, pregnant and volunteers who are not available to participate in all stages of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alterations in telomere content influenced by continuous aerobic training and interval aerobic training. The telome content will be analyzed by quantitative real time polymerase chain reaction (qPCR). The data are expressed in relative values of 2-CT in which it is expected a difference of 0.15 between the group with exercise and without exercise; and 0.20 in the different types of aerobic exercise. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in hormone concentrations and endocrine parameters, body composition, quality of life, anxiety, depression and sexual function mediated by the different types of training. Hormonal and endocrine components will be assessed by chemiluminescence and body composition by absorptiometry method Dual Energy X-Ray absortiometry (DEXA), skin folds and bioelectrical impedance. The quality of life will be assessed using the SF-36 questionnaire, for anxiety and depression will be used the hospital anxiety and depression scale questionaire, for evaluation of sexual function will be used the female sexual function index. Improvement in hormonal and endocrine parameters, reducing body fat and improves and / or recovery of sexual function, emotional status (anxiety and depression) and quality of life, which may vary with the type of training. | — |
Countries
Brazil
Contacts
Public ContactRosana dos Reis
Faculdade de Medicina de Ribeirão Preto
Outcome results
None listed