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Comparison of two medium for semen freezing with addition of some components in order to improve the quality of spermatozoa of infertile men.

Comparison of two medium for semen cryopreservation regarding the effects of lipid supplementation and antioxidant action on sperm viability in men with altered seminal parameters: a randomized clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-785ghf
Enrollment
Unknown
Registered
2018-02-14
Start date
2016-02-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

63 samples of semen will be collected, that is, 63 men will participate in this research. Each sample collected will be divided into two aliquots, one for the control group, which will be frozen with
Other
C12.294.365.700

Sponsors

Faculdade de Medicina de Ribeirão Preto
Lead Sponsor
Invitra
Collaborator

Eligibility

Sex/Gender
Male
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Men aged 18-40 years; literate;sent to the accomplishment of the spermogram in the laboratory of Gynecology and Obstetrics; able to collect the semen by masturbation; accept to participate in the study by signing a Term of Free and Informed Consent

Exclusion criteria

Exclusion criteria: Semen volume smaller than or equal 1.5 ml; sperm concentration greater than 15 million / mL; progressive motility greater than 32%; azoospermia; history of cancer from any location; previous or current use of chemotherapeutics or other medications known to interfere with spermatogenesis.

Design outcomes

Primary

MeasureTime frame
Expected outcome 1: increase in the progressive motility of frozen spermatozoa with the cryoprotective medium tested in the design compared to the control group, verified by spermogram.;Expected outcome 2: reduction of DNA fragmentation of frozen spermatozoa with the cryoprotectant medium tested in the design compared to the control group, verified by the TUNEL test.

Secondary

MeasureTime frame
Secondary outcomes are not expected

Countries

Brazil

Contacts

Public ContactRosana dos Reis

Faculdade de Medicina de Ribeirão Preto

romareis@fmrp.usp.br+ 55 (16) 99992 5722

Outcome results

None listed

Source: REBEC (via WHO ICTRP)