Upper Extremity
Conditions
Interventions
The work is a single-blind randomized clinical trial and will be carried out with two groups. Experimental group (EG) that will carry out training with VR virtual reality using Nintendo Wii® associate
L01.224.160.875
E02.760.169.063.500
Sponsors
Universidade de Brasília
Secretaria de saúde do Distrito Federal
Eligibility
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria will be age under 75 and over 18 years old; diagnosis of Multiple Sclerosis confirmed by a neurologist according to the McDonald criteria, with more than two years of evolution; a score between 3.5 and 6.5 on the Expanded Kurtzke Disability Status Scale (EDSS); no outbreaks in the last 6 months, before the start of the study; presence of mild to moderate cognitive impairment with a minimum score of 18 points on the Montreal Cognitive Assessment; absence of depression, considering the Beck Depression Inventory test, with a score of up to 13 points.
Exclusion criteria
Exclusion criteria: Exclusion criteria will be the presence of illnesses such as psychiatric, other neurological diseases or musculoskeletal disorders that may impede training; be using a course of steroids, whether orally or intravenously, in the last six months prior to the evaluation; be undergoing treatment with botulinum toxin on the date the clinical trial begins or in the six months before the start of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find an improvement in manual dexterity verified through the Nine hole peg test and the Box in block test, based on a reduction greater than 10% in the execution time in the pre and post test measurements in the experimental group; no difference is expected in handgrip strength verified by the handgrip test, with a difference of less than 5% from pre- to post-test in both groups; and improvement of functional activities verified by the Testd’ Evaluation de la performance des Membres Supérieurs des Personnes Âgées, based on a reduction greater than 5% in execution time. | — |
Secondary
| Measure | Time frame |
|---|---|
| An increase in processing speed, improvement in working memory and visuospatial skills is expected, as evidenced by higher scores on the Symbol Digit Modalities Test, Digit Span, California Verbal Learning Test–2nd ed and Rey-Osterrieth Complex Figure Test-A, with a variation of more than 5% between the pre- and post-test. | — |
Countries
Brazil
Contacts
Public ContactThiara Mariano
Universidade de Brasília
Outcome results
None listed