Alcohol-induced disorders Chemically-induced disorders
Conditions
Interventions
This is an open-label, non-randomized clinical trial without a control group, which seeks to evaluate the feasibility, safety, and effectiveness of using ayahuasca as an adjunct in the treatment of al
Sponsors
Universidade Federal de São Paulo
Centro de Atenção Integrada à Saúde Mental - CAISM
Eligibility
Age
25 Years to No maximum
Inclusion criteria
Inclusion criteria: Men and women aged 25 or older; currently diagnosed with alcohol use disorder; concerned about their drinking habit; with preserved cognitive abilities; and with a family member or friend who can pick them up after ayahuasca sessions
Exclusion criteria
Exclusion criteria: presence of kidney liver heart or esophageal diseases; presence of psychiatric symptoms (acute psychosis suicidal ideation bipolar disorder or severe symptoms of depression or anxiety); current use of selective serotonin reuptake inhibitor drugs or monoamine oxidase inhibitors at the time of the study; current use of natrexone disulfiram acomprosate methylphenidate or baclofen; clinical indication for hospitalization; clinical indication for the treatment of alcohol withdrawal symptoms
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A reduction in alcohol consumption is expected, assessed using a daily consumption log. Data will be collected twelve weeks before the intervention and four, twelve, and twenty-four weeks after the intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected that indicators of improvement in cognitive functions and psychiatric symptoms will be found, assessed respectively through neuropsychological tests and self-report scales. | — |
Countries
BR
Contacts
Public ContactPaulo Morais
Universidade Federal de São Paulo
Outcome results
None listed