Hip artritis / Total hip replacement
Conditions
Interventions
Drug
E07.695.400.400
A sample was divided into two groups. The control group underwent total hip prosthesis of Non cemented as the usual protocol Used at the National Institute of Trauma - Orthopedics. The group case , wa
Sponsors
Instituto Nacional de Traumatologia e Ortopedia
Instituto Nacional de Traumatologia e Ortopedia
Eligibility
Age
15 Years to 90 Years
Inclusion criteria
Inclusion criteria: Primary total hip replacement
Exclusion criteria
Exclusion criteria: Prior surgery same Joint;infecton;congenital coagulopathies carriers acquired;intravascular coagulation Active;acute occlusive vasculopathy;Hypersensitivity components of the formula;chronic use of oral anticoagulants and corticosteroids;allergy background or faced to transfusion plasma;Carriers of chronic diseases;Patients with malignant neoplasias and autoimmune diseases;need for bone grafting;revision surgeries;no concordance with the written informed consent and informed
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of bleeding during the early post operative, verified by measuring the bleeding by the formula that uses the variation of hematocrit pre and post operative ;Blood loss was 1,163 mL in the control group and 652.9 mL in the treated group (p <0.0001).;Reduction in the need for postoperative blood transfusion, verified by the volume of red blood cells used in the postoperative period.;The need for postoperative blood transfusion was lower in the treated patients (14.1% vs 32%, p = 0.001). In addition, a lower volume of packed red blood cells was used in the treated group (300 mL) than in the control group (600 mL) (p <0.0001). | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction of the fall in the value of postoperative Hb and Ht.;In the treated group, there was a reduction of 12.9% in the Hb value and 13.1% in the postoperative Ht, whereas in the control group there was a 23% decrease in the Hb value and 22.7% in the Ht value Postoperative (p <0.0001).;Reduction in hospital stay time in the treated group.;Although the median hospitalization time was the same in both groups, in the control group the variation in hospitalization time was 3 to 5 days, while in the treated group it was 3 to 7 days (p = 0.0001 ). | — |
Countries
Brazil
Contacts
Public ContactOsamu Kimura
Instituto Nacional de Traumatologia e Ortopedia
Outcome results
None listed