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Evaluation of periodontal treatment in patients with head and neck cancer

Longitudinal evaluation of response to periodontal therapy in patients with head and neck cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-74w9255
Enrollment
40
Registered
2026-05-12
Start date
2023-08-10
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and Neck Neoplasms

Interventions

This is a randomized, longitudinal, non-blinded clinical study. The 40 patients will be recruited on a rolling basis from the clinical dentistry services of the Clementino Fraga Filho University Hospi

Sponsors

Universidade Federal do Rio de Janeiro
Lead Sponsor
Faculdade de Odontologia da Universidade Federal do Rio de Janeiro
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients to be included must be over 18 years of age; of both sexes; multiethnic; have a minimum of eight teeth; cancer patients must have planned radiotherapy treatment in the head and neck region, provided that the oral cavity is included in the radiation field in External Beam Radiotherapy and Brachytherapy modalities, with irradiation between 50 and 70 Gray

Exclusion criteria

Exclusion criteria: Cancer patients will not be included if the interval between the first dental consultation and the start of radiotherapy is insufficient for evaluation and initiation of the necessary dental treatment; all patients, cancer patients or not, who have used bisphosphonates or other antiresorptive medications in the last 12 months and antibiotics in the last 3 months will be excluded

Design outcomes

Primary

MeasureTime frame
It was observed that the values ??of periodontal indices, such as plaque index, dental calculus, gingival bleeding, bleeding on probing, and suppuration, decreased consistently over time in both groups: patients with periodontitis and patients with cancer, with the bleeding on probing and gingival bleeding indices reaching values ??compatible with periodontal health (<10% of sites), verified by the periodontogram method, between the pre- and post-intervention periods.

Secondary

MeasureTime frame
No secondary outcomes are expected.

Countries

BR

Contacts

Public ContactNatalia De Lucena

Faculdade de Odontologia da Universidade Federal do Rio de Janeiro

natiollu@hotmail.com+55(024)992238508

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Jun 11, 2026