Temporomandibular Joint Disorders, Otoneurological Diseases, Quality of Life, Bruxism
Conditions
Interventions
3 groups will be formed, where each will be composed of 33 patients
group A: botulinum toxin type A will be applied
group B: 2% lidocaine without vasoconstrictor
and group C (placebo): 0.9% saline solution. Both doctors and patients will be blind as to the substance to be applied. After this stage, the first application of botulinum toxin, lidocaine or saline
Drug
HP3.073.433.101
Sponsors
Hospital Universitário Professor Edgard Santos/UFBA
Hospital Universitário Professor Edgard Santos/UFBA
Eligibility
Age
15 Years to 100 Years
Inclusion criteria
Inclusion criteria: Temporomandibular joint disorder diagnosis; otoneurologic symptoms for at least three months; at least 15 years of age; both genders; no current treatment for temporomandibular disorder or otoneurologic disease.
Exclusion criteria
Exclusion criteria: Allergy to lidocaine or botulinum toxin; anyone who changed therapies during the study to avoid false-positive; imunossupressed patients; diabetes mellitus; cognitive impairment; pregnancy or breast feeding; psychiatric disorders; skin conditions; clotting disturbances; neuromuscular diseases; using clacium channel blokers; antibiotics (aminoglycosides); cyclosporin; chloroquines; hydroxichloroquine; D-penicillamine; or anu=y other substance that interferes with neuromuscular transmission; Myasthenia gravis; Eaton Lambert syndrome; Amyotrophic sclerosis; or any disturbances that promote periferal neuromuscular dysfunction; oral anticoagulante; derivates from acetylsalicylic acid; derivates from vitemin E ou Ginko Biloba
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome was a reduction of at least 30% in the intensity of tinnitus determined through a questionnaire, at any intensity when compared to the initial condition, to verify whether the outcome actually happened. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected | — |
Countries
Brazil
Contacts
Public ContactIza Cristina de Castro
Hospital Universitário Professor Edgard Santos/UFBA
Outcome results
None listed